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Table 1 Clinical and biochemical characteristics in normotensive controls and hypertension patients

From: EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population

 

Normotensive controls

Hypertension group

Adjusted

(n = 1605)

(n = 541)

P-value

Age (year)

48.0 ± 10.9

54.3 ± 11.6**

BMI (kg/m2)

23.7 ± 2.91

25.4 ± 3.20**

Weight (kg)

63.0 ± 10.2

68.1 ± 11.9**

0.092

Waist (cm)

83.5 ± 7.79

87.8 ± 8.70**

0.690

Waist hip ratio

0.88 ± 0.06

0.90 ± 0.06**

0.130

Systolic BP (mmHg)

116.4 ± 11.5

138.5 ± 15.3**

< 0.001

Diastolic BP (mmHg)

72.7 ± 8.72

87.4 ± 10.7**

< 0.001

Triglyceride (mg/dL)a

119.7 ± 73.9

148.4 ± 87.5**

0.005

Total cholesterol (mg/dL)a

198.0 ± 36.0

198.3 ± 36.0

0.017

HDL cholesterol (mg/dL)a

53.9 ± 13.5

50.4 ± 12.8**

0.450

LDL cholesterol (mg/dL)a

121.0 ± 32.7

119.1 ± 32.7

0.050

Apolipoprotein A-I (mg/dL)a

156.1 ± 28.2

155.4 ± 27.9

0.023

Apolipoprotein B (mg/dL)a

104.4 ± 29.3

104.6 ± 27.7

0.049

Glucose (mg/dL)a

95.7 ± 20.7

103.9 ± 25.8**

0.002

Insulin (μIU/dL)a

9.08 ± 4.66

9.83 ± 5.76*

0.609

HOMA-IRa

2.15 ± 1.29

2.55 ± 2.03**

0.143

LDL particle size (nm)a

23.9 ± 1.07

23.9 ± 0.80

0.327

  1. Mean  ±  SD. atested by logarithmic transformation. *P < 0.05, **P < 0.001 derived from an independent t-test between two groups. Adjusted P-value derived after adjusting for age, sex, and BMI