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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Role of disturbed fatty acids metabolism in the pathophysiology of diabetic erectile dysfunction

Fig. 1

Hypothetical interaction between disturbed FAs metabolism and IR leading to impaired penile erection. SFAs, Saturated Fatty Acids; IR, Insulin Resistance; PI3-kinase, Phosphatidylinositol 3-Kinase; SREBP, Sterol Regulatory Element Binding Protein; Akt, Protein kinase B; eNOS, Endothelial Nitric Oxide Synthase; PGE1, Prostaglandin E1; NO, Nitric Oxide; GPCR, G-Protein-Coupled Receptor; ATP, Adenosine Triphosphate; cAMP, cyclic Adenosine Monophosphate; GTP, Guanosine Triphosphate; cGMP, cyclic Guanosine Monophosphate; Ca2+, Calcium; VSMCs, Vascular Smooth Muscle Cells; (), Increase; (), Decrease

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