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Table 4 Erythrocytes fatty acid profiles of the study population determined by gas chromatography

From: Role of disturbed fatty acids metabolism in the pathophysiology of diabetic erectile dysfunction

Fatty Acids (nomenclature) Name Patients with VED (%) (n = 72) Patients w/o VED (%) (n = 78) Controls (%) (n = 88)
C12: 0 Lauric acid 0.21 ± 0.12 0.19 ± 0.11 0.21 ± 0.13
C13: 0 Tridecylic acid 0.79 ± 0.53** 0.47 ± 0.45 0.53 ± 0.35
C14: 0 Myristic acid 4.12 ± 2.50*** 3.03 ± 2.09* 2.57 ± 2.30
C15: 0 Pentadecylic acid 1.07 ± 0.69*** 0.75 ± 0.45* 0.63 ± 0.51
C16: 0 Palmitic acid 28.82 ± 5.75** 29. 25 ± 6.66** 25.87 ± 4.16
C18: 0 Stearic acid 11.93 ± 5.82*** 13.29 ± 5.18* 14.88 ± 5.15
C20: 0 Arachidic acid 0.24 ± 0.32 0.23 ± 0.13* 0.26 ± 0.31
C22: 0 Behenic acid 0.43 ± 0.41*** 0.35 ± 0.16** 0.27 ± 0.21
C23: 0 Tricosylic acid 0.59 ± 0.42 0.44 ± 0.28 0.60 ± 0.79
C24: 0 Lignoceric acid 2.06 ± 0.83** 1.75 ± 1.14 1.42 ± 1.19
C26: 0 Cerotic acid 5.47 ± 2.28*** 3.21 ± 3.05** 3.72 ± 2.81
Σ SFA   55.70 ± 9.4** 52.84 ± 7.1 51,01 ± 8.7
C14:1 cis-9 (n-5) Myristoleic acid 1.33 ± 0.71** 0.98 ± 0.44*** 1.60 ± 0.56
C16:1 cis-9 (n-7) Palmitoleic acid 0.56 ± 0.51 0.60 ± 0.54 0.57 ± 0.47
C18:1 cis-9 (n-9) Oleic acid 10.96 ± 4.18*** 13.14 ± 3.31* 14.53 ± 3.65
C18:1 cis 11(n-7) Vaccenic acid 1.31 ± 0.30 1.39 ± 0.38 1.47 ± 0.49
C20:1 cis11 (n-9) Eicosenoic acid 0.16 ± 0.13*** 0.22 ± 0.18* 0.26 ± 0.17
C22:1 cis13(n-9) Erucic acid 0.45 ± 0.21 0.50 ± 0.21 0.54 ± 0.87
C24:1 (n-9) Nervonic acid 1.70 ± 0.59*** 1.61 ± 0.97*** 3.00 ± 1.31
Σ MUFA   16.50 ± 4.12*** 18.43 ± 3.65*** 21.00 ± 3.88
Omega 3 family (n-3)
 C18:3 cis9,12,15 α-linolenic acid 0.66 ± 0.34*** 0.63 ± 0.27*** 0.51 ± 0.28
 C20:3 cis11,14,17 Eicosatrienoic acid 1.43 ± 0.48 1.80 ± 0.83* 1.61 ± 0.95
 C20:5 EPA Eicosapentaenoic acid 0.52 ± 0.26*** 1.26 ± 1.02 1.54 ± 1.92
 C22:6 DHA Docosahexaenoic acid 2.00 ± 1.39*** 2.27 ± 1,21*** 3.13 ± 1.20
Omega 6 family (n-6)
 C18:2 cis9,12 Linoleic acid 12.05 ± 4.46*** 10.40 ± 3.20** 9.40 ± 5.21
 C18:3 cis6,9,12 γ-linolenic acid 0.16 ± 0.17* 0.19 ± 0.14 0.17 ± 0.11
 C20:3 cis8,11,14 Dihomo-γlinolenic acid 0.18 ± 0.09*** 0.28 ± 0.16 0.38 ± 0.27
 C20:4 Arachidonic acid 10.75 ± 3.09* 11.43 ± 2.38*** 9.25 ± 3.36
 Σ PUFA   27.79 ± 5.06 28.42 ± 4.11 26.03 ± 5.85
 Σ UFA   44.30 ± 5.75** 47.16 ± 6.03 47.03 ± 6.75
Desaturation index
 C20:4/C20:3 (Δ5D)   77.03 ± 51.26*** 54.18 ± 40.75* 47.99 ± 43.92
 C18:3/C18:2n-6 (Δ6D)   0.015 ± 0.016** 0.020 ± 0.015 0.023 ± 0.021
 C16:1/C16:0 (Δ9D-16)   0.02 ± 0.02 0.02 ± 0.02 0.02 ± 0.01
 C18:1/C18:0 (Δ9D-18)   1.18 ± 0.87 1.17 ± 0.66 1.17 ± 0.71
 C24:1/C18:1   0.18 ± 0.11* 0.12 ± 0.08*** 0.22 ± 0.12
 C18:0/C16:0   0.41 ± 0.21*** 0.48 ± 0.21** 0.57 ± 0.17
  1. Data obtained by GC are expressed as relative values (%): mean % of total FAs ± SD; Σ SFA, sum of saturated fatty acids; Σ MUFA, sum of monounsaturated fatty acids; Σ PUFA, sum of polyunsaturated fatty acids; Σ UFA, sum of unsaturated fatty acids; C20:4/C20:3, Δ5 desaturation index; C18:3/C18:2, Δ6 desaturation index; C16:1/C16:0 and C18:1/C18:0, Δ9 desaturation index; C24:1/C18:1 and C18:0/C16:0, elongation index; w/o, without
  2. *P < 0.05; **P < 0.01 and ***P < 0.001 compared to controls. The Mann-Whitney test with Bonferroni correction was used