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Table 3 Fatty acid composition of triglyceride in periuterine adipose tissue of Fischer 344 rats

From: Chemotherapy diminishes lipid storage capacity of adipose tissue in a preclinical model of colon cancer

Fatty acids (% total) REF TUM 1- Cycle 2- Cycles
C16:0 20.6 ± 0.5a 19.7 ± 0.3a 20.0 ± 0.4a 17.9 ± 0.7b
C16:1 3.9 ± 0.2a 3.6 ± 0.1a 3.4 ± 0.2a 2.6 ± 0.3b
C18:0 6.0 ± 0.3a 6.9 ± 0.2a 6.7 ± 0.1a 7.9 ± 0.4a
C18:1 41.3 ± 2.1a 42 ± 1a 41.3 ± 0.6a 44.3 ± 0.9a
C18:2n6 22.3 ± 1.6a 22.0 ± 0.7a 23.4 ± 0.5a 22.5 ± 0.4a
C18:3n3 1.6 ± 0.1a 1.7 ± 0a 1.3 ± 0b 1.2 ± 0.1b
C20:4n6 0.8 ± 0.1a 0.7 ± 0a 0.6 ± 0a 0.6 ± 0a
C20:5n3 ND ND ND ND
C22:6n3 0.4 ± 0.1a 0.4 ± 0a 0.3 ± 0a 0.3 ± 0a
ΣSFA 28.3 ± 0.3a 28.2 ± 0.2a 28.3 ± 0.3a 27.3 ± 0.3a
ΣMUFA 45.7 ± 2a 46.1 ± 1a 45.2 ± 0.6a 47.4 ± 0.7a
Σn-6/n-3 11.2 ± 0.6a 10.3 ± 0.2a 13.6 ± 0.5b 14.7 ± 0.7b
Σn-6 23.8 ± 1.7a 23.4 ± 0.8a 24.7 ± 0.5a 23.7 ± 0.4a
Σn-3 2.2 ± 0.3a 2.3 ± 0.1a 1.8 ± 0.1b 1.6 ± 0.1b
  1. Triglyceride fatty acids in periuterine adipose tissue of Fischer 344 rats bearing the Ward colorectal carcinoma receiving 1- or 2- cycles of chemotherapy. Healthy rats were used a reference for comparison (REF). Mean ± SEM, Kruskall test was used to determine significant differences between groups. Different superscripts (a, b) indicate significant differences between groups (P < 0.05); (n = 6–8/group). Abbreviations: SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturatsed fatty acids; REF, Reference; TUM, Tumour-bearing; ND, not determined