Skip to main content


Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells

Fig. 2

Heatmap illustrating log2-expression intensities of the genes that are differentially expressed after treatment of MiaPaCa-2 cells with simvastatin, FPP, GGPP, or their combinations. Only the differentially transcribed genes with at least two-fold change in expression intensity and q < 0.05 are shown. The list and sequence of the genes correspond to those stated in the Additional file 1: Table S4. Simva = simvastatin; FPP = farnesyl pyrophosphate; GGPP = geranylgeranyl pyrophosphate

Back to article page