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Table 4 Distributions of alleles and genotypes between T2DM patients and control subjects in females

From: Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population

Polymorphism

T2DM

Non-diabetic

Unadjusted Pa

Adjusted OR(95% CI)/Pb

rs3806318

n = 363

n = 393

  

 AA

287(79.1%)

302(76.9%)

0.941

1

 AG

73(20.1%)

87(22.1%)

 

0.990(0.558–1.7561)/0.972

 GG

3(0.8%)

4(1.0%)

 

1.062(0.643–1.753)/0.816

 A

647(89.1%)

691(87.9%)

0.746

1

 G

79(10.9%)

95(12.1%)

 

1.053(0.805–1.378)/0.704

rs1327118

n = 361

n = 390

  

 CC

293(81.2%)

300(76.9%)

0.644

1

 CG

65(18.0%)

83(21.3%)

 

0.849(0.522–1.381)/0.509

 GG

3(0.8%)

7(1.8%)

 

1.240(0.824–1.868)/0.303

 C

651(90.2%)

683(87.6%)

0.627

1

 G

71(9.8%)

97(12.4%)

 

1.112(0.868–1.425)/0.402

  1. T2DM type 2 diabetes mellitus
  2. aP-values were obtained by chi-square tests
  3. bP-values were obtained by logistic regression analysis adjusted for age, BMI
  4. P values in boldface are significant