Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats

Table 9 Grades of glomerular and epithelial cells of the proximal tubules necrosis in rat kidney

Pathologic grading of glomerular and epithelial cells of the proximal tubules necrosis
Groups	Zero	I	II	III	IV	N	P value vs Control	P value vs CCl₄
Control	10	0	0	0	0	10	–
CCl₄^***	0	2	2	3	3	10	P < 0.001	–
SL/CCl₄^###	8	2	0	0	0	10	ns	P < 0.001
MpEO^a/CCl₄	0	2	5	3	0	10	P < 0.05	ns
MpEO^b/CCl₄^#	6	4	0	0	0	10	ns	P < 0.05
MpEO^c/CCl₄^###	7	3	0	0	0	10	ns	P < 0.001
MpEO^c	9	1	0	0	0	10	ns	P < 0.001

^aMpEO (5 mg/kg BW), ^bMpEO (15 mg/kg BW), ^cMpEO (40 mg/kg BW), SL: Silymarin (50 mg/kg BW)

ISSN: 1476-511X