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Table 1 Characteristics of older adults newly prescribed and not prescribed ezetimibe within six months of a hospital discharge for an AMI

From: Ezetimibe prescriptions in older Canadian adults after an acute myocardial infarction: a population-based cohort study

 

No Ezetimibe Prescription N = 69, 895

New Ezetimibe Prescription N = 1230

Standardized Difference

Age

N

%

N

%

 

Mean (SD)

78.42

7.72

74.84

6.43

50%

Median (IQR)

78

(72–84)

74

(69–79)

 

Female

31, 995

45.8%

559

45.4%

1%

Rural location

11, 497

16.4%

224

18.2%

5%

Income quintile

 1 (lowest)

15, 454

22.1%

243

19.8%

6%

 2

14, 762

21.1%

253

20.6%

1%

 3

14, 028

20.1%

257

20.9%

2%

 4

13, 162

18.8%

256

20.8%

5%

 5 (highest)

12, 489

17.9%

221

18.0%

0%

Long-term care

3587

5.1%

< 6

< 0.5%

–

Year of hospital discharge

 2005

8390

12.0%

131

10.7%

4%

 2006

7678

11.0%

174

14.1%

10%

 2007

7974

11.4%

187

15.2%

11%

 2008

7786

11.1%

121

9.8%

4%

 2009

7537

10.8%

114

9.3%

5%

 2010

7585

10.9%

127

10.3%

2%

 2011

7530

10.8%

148

12.0%

4%

 2012

7572

10.8%

117

9.5%

4%

 2013

7843

11.2%

111

9.0%

7%

Rostered to a family physician

55, 396

79.3%

1015

82.5%

8%

Comorbiditiesa

Coronary artery disease

27, 838

39.8%

509

41.4%

3%

Stroke/Transient ischemic attack

3012

4.3%

40

3.3%

5%

Diabetes

64, 973

93.0%

1102

89.6%

12%

Peripheral vascular disease

2199

3.1%

36

2.9%

1%

Chronic kidney disease

8809

12.6%

123

10.0%

8%

Dialysis

1080

1.5%

10

0.8%

7%

Hypertension

64, 745

92.6%

1094

88.9%

13%

Liver disease

1905

2.7%

32

2.6%

1%

Congestive heart failure

14, 634

20.9%

146

11.9%

24%

Coronary revascularization

2555

3.7%

71

5.8%

10%

Charlson comorbidity index

 0 (no hospitalizations)

46, 300

66.2%

921

74.9%

19%

 1

7498

10.7%

114

9.3%

5%

 2

6248

8.9%

95

7.7%

4%

 3 or higher

9849

14.1%

100

8.1%

19%

Healthcare Utilizationb

Visit to a family physician

66, 325

94.9%

1165

94.7%

1%

Visit to cardiologist

32, 321

46.2%

559

45.4%

2%

Visit to endocrinologist

5025

7.2%

106

8.6%

5%

Visit to internist

24, 020

34.4%

393

32.0%

5%

Evidence of at least 1 cholesterol test

35, 060

50.2%

797

64.8%

30%

Baseline medicationsc

Any statin

30, 329

43.4%

556

45.2%

4%

Statin intensityd

 Low

2335

3.3%

29

2.4%

5%

 Moderate

20, 626

29.5%

314

25.5%

9%

 High

6857

9.8%

205

16.7%

20%

 Other

511

0.7%

8

0.7%

0%

Fibrates

1430

2.0%

56

4.6%

15%

Thienopyridines

1576

2.3%

21

1.7%

4%

Beta-blocker

24, 614

35.2%

438

35.6%

1%

Angiotensin converting enzyme inhibitor

25, 701

36.8%

415

33.7%

6%

Angiotensin receptor blocker

14, 131

20.2%

303

24.6%

11%

  1. Unless indicated, data presented as number and percentage
  2. Standardized differences > 10% are considered meaningful
  3. Cell sizes < 6 are not presented for patient privacy
  4. aComorbidities were ascertained in the 5 years prior to their hospitalization for an AMI
  5. bHealthcare utilization was ascertained in the 1 year prior to their hospitalization for an AMI
  6. cBaseline medications were examined in the 120 days prior to their AMI hospitalization
  7. dIntensity of statin therapy was categorized based upon guideline recommendations from the American College of Cardiology