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Table 3 Multinomial logistic analysis of the risk factors for T2DM

From: Circulating PCSK9 levels and 2-hPG are positively correlated in metabolic diseases in a Chinese Han population

Variables

Model

IGR

T2DM

  

OR(95%CI)

P

OR(95%CI)

P

Age

1

0.995(0.775–1.277)

0.967

0.938 (0.723–1.216)

0.628

(10 years)

2

1.008 (0.782–1.300)

0.949

0.967 (0.743–1.259)

0.803

Sex

1

0.892 (0.577–1.379)

0.606

0.977 (0.620–1.541)

0.921

2

0.874 (0.561–1.361)

0.551

1.019 (0.641–1.619)

0.936

BP

1

1.705 (1.084–2.680)

0.021

2.595 (1.627–4.139)

<0.001

(mmHg)

2

1.641 (1.037–2.596)

0.034

2.483 (1.549–3.982)

<0.001

BMI

1

2.411 (1.490–3.902)

<0.001

2.154 (1.309–3.545)

0.003

(kg/m2)

2

2.450 (1.505–3.986)

<0.001

2.044 (1.233–3.389)

0.006

WC

1

0.836 (0.424–1.648)

0.604

0.796 (0.395–1.604)

0.523

(cm)

2

0.906 (0.455–1.801)

0.778

0.809 (0.397–1.647)

0.558

HC

1

0.990 (0.942–1.040)

0.683

0.983 (0.933–1.036)

0.525

(cm)

2

0.984 (0.936–1.035)

0.526

0.978 (0.927–1.032)

0.416

WHR

1

1.026 (0.588–1.793)

0.927

1.279 (0.716–2.287)

0.406

2

1.003 (0.572–1.760)

0.992

1.222 (0.679–2.200)

0.504

HR

1

1.040 (1.020–1.060)

<0.001

1.041 (1.021–1.062)

<0.001

(per min)

2

1.036 (1.016–1.057)

<0.001

1.039 (1.018–1.060)

<0.001

HDL-C

1

___

___

___

___

(mmol/l)

2

1.661 (1.023–2.698)

0.040

0.777 (0.462–1.304)

0.339

LDL-C

1

___

___

___

___

(mmol/L)

2

1.268 (0.661–2.436)

0.475

1.796 (0.894–3.608)

0.100

TC

1

___

___

___

___

(mmol/L)

2

1.012 (0.460–2.229)

0.976

0.942 (0.413–2.151)

0.887

TG

1

___

___

___

___

(mmol/L)

2

2.411 (1.266–4.591)

0.007

2.383 (1.242–4.572)

0.009

PCSK9

1

1.008 (1.001–1.015)

0.019

1.018 (1.011–1.025)

<0.001

(ng/ml)

2

1.007 (1.000–1.014)

0.059

1.017 (1.010–1.025)

<0.001

  1. Model1: age, sex, BP, BMI, WC, HC, WHR, HR and PCSK9 were in the model
  2. Model2: Model 1 plus HDL-C, LDL-C, TC, TG
  3. BP blood pressure, BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, HR heart rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride, PCSK9 Preprotein convertase subtilisin/kexin type 9