Table 1 Clinical and laboratory data for 816 normotensive subjects divided into two groups according to their gender
Variables | Men (n = 476) | Women (n = 340) | All subjects (n = 816) | p value |
|---|---|---|---|---|
Age(years) | 40.5 ± 7.4 | 37.2 ± 8.1 | 39.1 ± 7.8 | < 0.001 |
Education(years) | 0.211 | |||
 Low(<9y) | 70(14.7%) | 64(18.8%) | 134(16.4%) | |
 Middle(9-12y) | 178(37.4%) | 120(35.3%) | 298(36.5%) | |
 High(>12y) | 228(47.9%) | 156(45.9%) | 384(47.1%) | |
Family income(CNY/y) | 0.683 | |||
  < 30,000 | 82(17.3%) | 59(17.4%) | 141(17.3%) | |
 30,000-100,000 | 274(57.7%) | 187(55.0%) | 461(56.6%) | |
  > 100,000 | 119(25.0%) | 94(27.6%) | 213(26.1%) | |
Physical activity | 0.760 | |||
 Low | 200(42.0%) | 155(45.6%) | 355(43.5%) | |
 Intermediate | 178(37.4%) | 112(32.9%) | 290(35.5%) | |
 High | 98(20.6%) | 73(21.5%) | 171(21.0%) | |
BMI(kg/m2) | 24.8 ± 2.3 | 21.0 ± 2.2 | 23.2 ± 2.9 | < 0.001 |
Smoking (%) | 163(34.2%) | 13(3.8%) | 176(21.6%) | < 0.001 |
Drinking (%) | 139(29.2%) | 19(5.6%) | 158(19.4%) | < 0.001 |
SBP(mm Hg) | 126.2 ± 9.2 | 125.4 ± 9.6 | 126.0 ± 9.4 | 0.245 |
DBP(mm Hg) | 75.0 ± 7.1 | 75.5 ± 7.1 | 75.2 ± 7.1 | 0.344 |
PP(mm Hg) | 51.2 ± 9.5 | 49.9 ± 9.6 | 50.7 ± 9.5 | 0.065 |
MAP(mm Hg) | 92.0 ± 6.5 | 92.1 ± 6.6 | 92.0 ± 6.5 | 0.827 |
HR(bpm) | 72.6 ± 7.2 | 71.7 ± 7.3 | 72.2 ± 7.2 | 0.083 |
ALT(U/L) | 26.5 ± 15.9 | 28.0 ± 16.4 | 27.1 ± 16.1 | 0.196 |
AST(U/L) | 22.8 ± 11.3 | 22.1 ± 9.5 | 22.5 ± 10.6 | 0.391 |
GGT(U/L) | 29.6 ± 18.4 | 29.5 ± 17.7 | 29.6 ± 18.1 | 0.957 |
BUN(mmol/L) | 5.18 ± 1.23 | 4.99 ± 1.13 | 5.10 ± 1.19 | 0.021 |
Cr(ummol/L) | 68.4 ± 10.0 | 66.7 ± 10.4 | 67.7 ± 10.2 | 0.016 |
UA(ummol/L) | 290.8 ± 93.1 | 291.9 ± 94.8 | 291.3 ± 93.7 | 0.874 |
FBG(mmol/L) | 5.11 ± 0.61 | 5.05 ± 0.61 | 5.09 ± 0.61 | 0.186 |
TC(mmol/L) | 4.81 ± 0.77 | 4.76 ± 0.79 | 4.79 ± 0.78 | 0.466 |
TG(mmol/L) | 1.68 ± 0.72 | 1.62 ± 0.73 | 1.65 ± 0.73 | 0.259 |
LDL-C(mmol/L) | 3.00 ± 0.76 | 2.95 ± 0.77 | 2.98 ± 0.76 | 0.349 |
HDL-C(mmol/L) | 1.21 ± 0.30 | 1.20 ± 0.26 | 1.21 ± 0.29 | 0.844 |
sdLDL-C(mmol/L) | 0.72 ± 0.28 | 0.66 ± 0.26 | 0.70 ± 0.27 | 0.004 |
ApoB(g/L) | 0.95 ± 0.26 | 0.94 ± 0.25 | 0.94 ± 0.26 | 0.390 |
ApoA-1(g/L) | 1.21 ± 0.31 | 1.24 ± 0.30 | 1.23 ± 0.31 | 0.102 |
TC/HDL-C | 4.21 ± 1.25 | 4.14 ± 1.16 | 4.18 ± 1.21 | 0.434 |
TG/HDL-C | 1.48 ± 0.79 | 1.39 ± 0.68 | 1.44 ± 0.75 | 0.12 |
LDL-C/HDL-C | 2.64 ± 0.95 | 2.57 ± 0.90 | 2.61 ± 0.93 | 0.312 |
sdLDL-C/HDL-C | 0.64 ± 0.35 | 0.58 ± 0.29 | 0.62 ± 0.33 | 0.011 |
ApoB/ApoA-1 | 0.81 ± 0.32 | 0.82 ± 0.30 | 0.82 ± 0.31 | 0.687 |
Baseline PWV(m/s) | 9.96 ± 0.84 | 9.83 ± 0.85 | 9.91 ± 0.84 | 0.03 |
Follow-up PWV(m/s) | 10.66 ± 1.19 | 10.45 ± 1.18 | 10.57 ± 1.19 | 0.01 |
△PWV(m/s) | 0.70 ± 0.55 | 0.62 ± 0.48 | 0.67 ± 0.52 | 0.02 |
PWV progression (%) | 93(19.5%) | 51(15.0%) | 144(17.6%) | 0.094 |
HT progression (%) | 82(17.2%) | 47(13.8%) | 129(15.8%) | 0.189 |
hs-CRP(mg/L) | 0.85 ± 0.21 | 0.64 ± 0.16 | 0.76 ± 0.19 | 0.004 |
TNF-α(pg/ml) | 3.03 ± 0.83 | 3.04 ± 0.81 | 3.04 ± 0.82 | 0.974 |
IL-6(pg/ml) | 2.70 ± 1.17 | 2.60 ± 1.15 | 2.66 ± 1.17 | 0.234 |