ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1

Table 2 Comparisons of clinical parameters amongst control, overweight and obese study subjects

VARIABLES	Control (n = 115) mean ± SEM	Overweight (n = 68) mean ± SEM	Obese (n = 146) mean ± SEM	P value
Cholesterol (mmol/L)	3.43 ± 0.04	4.19 ± 0.09	4.4 ± 0.07	0.0001
Triglyceride (mmol/L)	0.74 ± 0.02	1.082 ± 0.05	1.302 ± 0.04	0.0001
HDL (mmol/L)	1.32 ± 0.03	1.19 ± 0.04	1.07 ± 0.024	0.0001
LDL -cholesterol (mmol/L)	1.55 ± 0.05	2.07 ± 0.89	2.56 ± 0.06	0.0001
Leptin (ng/ml)	9.42 ± 0.48	17.51 ± 0.97	36.13 ± 1.67	0.0001
Fasting Insulin (pmol/L)	57.21 ± 2.09	72.23 ± 4.28	106.03 ± 3.07	0.0001
Fasting Glucose (mmol/L)	4.71 ± 0.041	5.051 ± 0.057	5.06 ± 0.05	0.0001

Values are mean ± SEM. Abbreviations: Values are mean ± SEM. Abbreviations: HDL: High-density lipoproteins; LDL: Low-density lipoprotein; SE: Standard Error of the Mean

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