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Table 3 Distribution of the genotypes, allele’s frequencies and odd ratio of the ADRB1 Arg389Gly polymorphism in control, overweight and obese subjects

From: ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1

Genotype

Control

T = 115

Overweight

T = 68

Obese

T = 146

χ2 Odds ratio (95% CI)

P- value

Genotype Frequency

 Arg\Arg

20 (17.4)

12 (17.6)

18 (12.3)

χ2

Ow = 0.08

Ob = 0.7

-Odds ratio (95% CI) Control vs OW 1.09(0.6–1.9)

-Odds ratio (95% CI) Control vs Obese 1.2(0.75–1.3)

P value for Odds ratio in control vs overweight: 0.8 and control vs obese:0.4

 Arg\Gly

45 (39.1)

25 (36.8)

57 (39)

 Gly\Gly

50 (43.5)

31 (45.6

71 (48.6)

Allele Frequency

 Allele Arg389

37.0%

36%

31.8%

Odds ratio (95% CI) Control vs OW

1.04 (0.67–1.6)

Odds ratio (95% CI) Control vs Obese1.25(0.9–1.8)

P = 0.86

 Allele Gly 389

63.o%

64%

68.2%

P = 0.22

  1. OW = Overweight; Ob = Obese; CI: Confidence interval; χ2: Chi square