Lipid profiles in French West Indies sickle cell disease cohorts, and their general population

Table 3 Lipid levels of SCA and SCC patients according to ACS, CVO and OTN history

	SCA						SCC
Characteristics and lipid levels	ACS n = 9	NoACS n = 88	VOC n = 14	NoVOC n = 83	OTN n = 30	NoOTN n = 67	OTN n = 15	NoOTN n = 47
Female sex	4 (44.4)	50 (56.8)	8 (57.1)	46 (55.4)	19 (63.3)	35 (52.2)	10(66.7)	31 (66.0)
WHR (cm/cm)	0.88 ± 0.02	0.86 ± 0.05	0.87 ± 0.05	0.86 ± 0.05	0.87 ± 0.05	0.86 ± 0.05	0.91 ± 0.04	0.84^* ± 0.07
Hematocrit (% ± SD)	23.6 ± 3.2	23.6 ± 3.7	25.7 ± 3.0	23.2^* ± 3.7	25.25 ± 3.04	22.85^** ± 3.69	30.33 ± 2.65	30.90 ± 2.98
Hemolytic Component	−0.05 ± 1.11	0.01 ± 0.99	− 0.46 ± 0.68	0.07 ± 1.02	− 0.35 ± 0.61	0.16 ^** ± 1.10	−0.07 ± 1.09	0.02 ± 0.98
TC (g/l)	1.25 ± 0.30	1.21 ± 0.30	1.23 ± 0.26	1.21 ± 0.30	1.25 ± 0.30	1.20 ± 0.29	1.44 ± 0.32	1.39 ± 0.32
HDL-C (g/l)	0.42 ± 0.13	0.36 ± 0.09	0.38 ± 0.09	0.36 ± 0.10	0.38 ± 0.09	0.36 ± 0.10	0.47 ± 0.14	0.44 ± 0.11
ApoA (g/l)	1.22 ± 0.28	1.09 ± 0.19	1.15 ± 0.16	1.10 ± 0.21	1.15 ± 0.21	1.11 ± 0.20	1.32 ± 0.27	1.22 ± 0.16
Non HDL-C > 1.30 (g/l)	1 (11.1)	5 (5.7)	1 (7.1)	5 (6.0)	3 (10.0)	3 (4.5)	4 (28.6)	3 ^*(6.5)
LDL-C (g/l)	0.64 ± 0.20	0.66 ± 0.24	0.64 ± 0.21	0.66 ± 0.24	0.68 ± 0.25	0.64 ± 0.23	0.83 ± 0.23	0.78 ± 0.24
ApoB (g/l)	0.58 ± 0.17	0.61 ± 0.19	0.57 ± 0.16	0.61 ± 0.19	0.63 ± 0.19	0.59 ± 0.18	0.69 ± 0.20	0.65 ± 0.19
TG (g/l)	1.06 ± 0.57	0.96 ± 0.37	1.03 ± 0.53	0.96 ± 0.37	0.96 ± 0.37	0.97 ± 0.40	0.80 ± 0.49	0.80 ± 0.42
TG ≥ 1.50 g/l	3 (33.3)	6 ^*(6.9)	3 (21.4)	6 (7.3)	3 (10.0)	6 (9.1)	1 (6.7)	3 (6.5)

Values represent n (and proportion) or mean result ± standard deviation (SD), unless otherwise indicated. Significance: ^*p < 0.05; ^**p < 0.01. ACS: acute chest syndrome positive history; NoACS: absence of ACS history; VOC: hospitalized vaso occlusive crisis positive history; NoVOC: absence of VOC history; OTN: Osteonecrosis positive history; NoOTN, absence of OTN history; WHR (waist over hips ratio), TC (total cholesterol), HDL-C (high density lipoprotein-cholesterol), LDL-C (low density lipoprotein- cholesterol), Non HDL-C (Non HDL-cholesterol); ApoA (apolipoprotein A), ApoB (apolipoprotein B), TG (triglycerides)

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