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Table 1 Anthropometric and routine laboratory parameters of study participants

From: Serum obestatin level strongly correlates with lipoprotein subfractions in non-diabetic obese patients

 

Obese (n = 50)

Control (n = 32)

P

Gender (F/M)

43 / 7

27 / 5

ns

Age (yrs)

44.20 ± 13.50

41.78 ± 5.97

ns

Body mass index (kg/m2)

41.96 ± 8.63

24.47 ± 2.51

< 0.001

Waist circumference (cm)

119.76 ± 16.87

83.62 ± 9.25

< 0.01

hsCRP (mg/l)

8.24 (3.2–13.09)

1.57 (0.6–2.94)

< 0.001

Fructose amine (μmol/l)

225.32 ± 27.95

229.0 ± 11.65

ns

Thyroid stimulating hormone (mU/l)

1.98 ± 0.98

1.93 ± 1.15

ns

Lipid parameters

 Triglyceride (mmol/l)

1.4 (1.1–2.0)

1.0 (0.75–1.39)

< 0.01

 Total cholesterol (mmol/l)

5.04 ± 0.83

5.07 ± 0.78

ns

 HDL-cholesterol (mmol/l)

1.36 ± 0.33

1.56 ± 0.46

< 0.05

 LDL-cholesterol (mmol/l)

3.17 ± 0.74

2.93 ± 0.52

ns

 Apolipoprotein A-I (g/l)

1.48 ± 0.24

1.68 ± 0.31

< 0.01

 Apolipoprotein B (g/l)

0.86 ± 0.20

0.94 ± 0.18

ns

 Lipoprotein (a) (mg/l)

248 (120–586)

70 (30–214)

< 0.001

Carbohydrate parameters

 Hemoglobin A1c (%)

5.76 ± 0.54

5.07 ± 0.33

< 0.001

 Fasting glucose (mmol/l)

4.90 ± 0.75

4.82 ± 0.48

ns

 OGTT 120 min

7.00 ± 2.01

  

 Fasting insulin (mU/l)

21.01 ± 15.91

 

 HOMA-IR

3.75 (2.4–6.52)

 

Inflammatory and oxidative markers

 Obestatin (μg/ml)

3.01 ± 0.5

3.29 ± 0.6

< 0.05

 Oxidized LDL (U/L)

46.8 ± 9.95

41.1 ± 9.57

< 0.01

 Paraoxonase activity (U/L)

64.72 (43.79–149.52)

83.03 (47.9–167.4)

ns

 Arylesterase activity (U/L)

121.61 ± 23.65

131.1 ± 28.75

ns

 Myeloperoxidase (ng/ml)

280 (148.3–386.3)

207.9 (125.8–265.2)

< 0.05

  1. Values are presented as mean ± standard deviation or median (lower quartile - upper quartile). Abbreviations: HDL high-density lipoprotein, hsCRP high sensitive C-reactive protein, LDL low-density-lipoprotein, OGTT oral glucose tolerant test, HOMA-IR homeostasis model assessment insulin resistance, ns non-significant