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Table 2 Concentration and ratio of lipoprotein subfractions in non-diabetic obese and lean participants

From: Serum obestatin level strongly correlates with lipoprotein subfractions in non-diabetic obese patients

 

Obese (n = 50)

Control (n = 32)

P

VLDL subfraction (mmol/l)

1.165 ± 0.17

0.868 ± 0.17

< 0.001

Midband (IDL) (mmol/l)

1.207 ± 0.31

1.505 ± 0.38

< 0.001

VLDL subfraction (%)

23.3 ± 2.5

17.1 ± 2.3

< 0.001

Midband (IDL) (%)

23.7 ± 3.6

29.6 ± 5

< 0.001

LDL subfractions

 Large LDL (mmol/l)

1.267 (1.06–1.603)

1.047 (0.827–1.344)

< 0.01

 Small-dense LDL (mmol/l)

0.091 (0.026–0.155)

0.026 (0–0.052)

< 0.001

 Mean LDL size (nm)

26.98 ± 0.31

27.26 ± 0.37

< 0.001

 Large LDL (%)

25.8 ± 4.1

21.1 ± 5.8

< 0.001

 Small-dense LDL (%)

1.96 ± 1.57

1.05 ± 2.26

< 0.05

HDL subfractions

 Large HDL (mmol/l)

0.284 (0.207–0.388)

0.453 (0.31–0.608)

< 0.001

 Intermediate HDL (mmol/l)

0.6594 (0.595–0.828)

0.749 (0.659–0.853)

< 0.05

 Small HDL (mmol/l)

0.336 (0.284–0.388)

0.284 (0.246–0.336)

< 0.01

 Large HDL (%)

22.5 ± 5.7

29.8 ± 9.0

< 0.001

 Intermediate HDL (%)

52.3 ± 3.4

50.8 ± 4.7

ns

 Small HDL (%)

25.2 ± 5.9

19.3 ± 5.3

< 0.001

  1. Values are presented as mean ± standard deviation or median (lower-upper quartiles)
  2. Abbreviations: HDL high-density lipoprotein, hsCRP high sensitive C-reactive protein, IDL intermediate density lipoprotein, LDL low-density-lipoprotein, OGTT oral glucose tolerant test, HOMA-IR homeostasis, VLDL very low-density lipoprotein