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Table 1 Dose response of anticancer properties of various compounds in Hela cells

From: Proteasome inhibitors modulate anticancer and anti-proliferative properties via NF-kB signaling, and ubiquitin-proteasome pathways in cancer cell lines of different organs

Concetrations

Thiostrepton

Ampicillin

Dexamethasone

2-Methoxyestradiol

δ-Tocotrienol

(−) Riboflavin

Ascorbic acid

Quercetin

Amiloride-HCL

(−)Corey lactone

Quinine Sulphate

in μM

1

2

3

4

5

6

7

8

9

10

11

MCa 0.0

43.0

46.0

33.0

33.0

46.0

43.0

43.0

45.0

55.0

55.0

45.0

MC + DMSOb 0.0

54.0 (100)c

43.0 (100)

34.0 (100)

34.0 (100)

41.0 (100)

42.0 (100)

40.0 (100)

56.0 (100)

54.0 (100)

54.0 (100)

55.0 (100)

2.5

51.0 (94)

41.0 (95)

26.0 (76)

21.0 (62)

26.0 (63)

40.0 (95)

33.0 (83)

46.0 (82)

41.0 (760)

49.0 (91)

52.0 (93)

5.0

36.0 (67)

38.0 (88)

22.0 (65)

16.0 (47)

24.0 (59)

40.0 (95)

32.0 (80)

45.0 (80)

37.0 (69)

45.0 (83)

40.0 (71)

10.0

13.0 (24)

36.0 (84)

23.0 (68)

12.0 (35)

13.0 (32)

34.0 (81)

27.0 (68)

42.0 (75)

28.0 (52)

47.0 (87)

24.0 (44)

20.0

11.0 (20)

33.0 (77)

20.0 (59)

9.0 (25)

11.0 (27)

32.0 (76)

28.0 (70)

27.0 (48)

31.0 (57)

45.0 (83)

15.0 (27)

40.0

9.0 (16)

30.0 (70)

22.0 (68)

7.0 (21)

9.0 (22)

29.0 (69)

24.0 (60)

23.0 (41)

35.0 (65)

42.0 (78)

11.0 (20)

80.0

0.0 (0)

32.0 (74)

22.0 (68)

3.0 (9)

10.0 (24)

27.0 (64)

22.0 (52)

20.0 (36)

31.0 (57)

36.0 (67)

4.0 (7)

  1. aMedium + Cells; bMedium + Cells + 0.2%DMSO (dimethyl sulphoxide); cPercentage of control values are in parentheses
  2. Boldfaced values signify the most effective doses
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