Lipoprotein turnover and possible remnant accumulation in preeclampsia: insights from the Freiburg Preeclampsia H.E.L.P.-apheresis study

Table 3 Turnover data calculated after first H.E.L.P. apheresis. As occurring or worsening edema during therapy interferes with calculating the plasma volume, only data from each patient’s first apheresis were considered (n = 6) for the calculation of apparent fractional catabolic rates (FCR’) and apparent synthetic rate (SR’). Each individual FCR’ and SR’ are given as mean calculated from all available blood samples after first apheresis, calculations were done according to Eqs. 2 and 3 (see methods for details)

Patient	Serum apoB		Serum cholesterol		LDL-cholesterol		Plasmavolume [1]	Body weight [kg]
	FCR’ (day⁻¹)	SR’ (mgkg^− 1day^− 1)	FCR’ (day^− 1)	SR’ (mgkg^− 1day^− 1)	FCR’ (day^− 1)	SR’ (mgkg^− 1day^− 1)	Plasmavolume [1]	Body weight [kg]
1	0.46	21.9	0.78	76.9	0.35	19.2	3.034	81
2	0.51	18.5	0.70	48.4	0.12	4.7	3.009	84
3	0.34	15.6	0.27	23.8	0.24	12.3	2.584	71
4	1.04	35.5	1.41	125.6	0.67	27.0	2.504	61
5	0.82	31.3	0.76	64.9	0.62	21.7	2.872	80
6	0.98	30.6	1.09	104.5	0.60	17.7	2.956	59
Mean ± SD	0.69 ± 0.29	25.6 ± 8.0	0.84 ± 0.39	74.0 ± 37.0	0.43 ± 0.23	17.1 ± 7.7

ISSN: 1476-511X