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Table 4 The values of inflammatory markers, anti-oxidative parameters and lipid peroxidation markers in CAD patients and controls

From: Correlation of trans fatty acids with the severity of coronary artery disease lesions

 

Controls

n = 120

CAD patients

n = 111

Inflammatory markers (plasma)

 TNF-α pg/mL

3.22 ± 3.27

7.40 ± 3.38**

 IL-6 pg/mL

4.39 ± 1.50

7.12 ± 3.90**

 hs-CRP (mg/L)

1.22 ± 0.95

3.03 ± 2.26**

Antioxidative parameters

 FRAP μMol/L (plasma)

905.99 ± 216.76

842.00 ± 171.15*

 Thiol SH μMol/L (plasma)

308.70 ± 55.04

172.13 ± 65.55**

 Catalase (U/g HB) (RBCs)

73.83 ± 59.82

299.55 ± 11.00**

 GPX (U/g HB) (RBCs)

41.51 ± 9.70

32.55 ± 5.97**

 SOD U/g HB (RBCs)

2103.26 ± 286.12

1531.66 ± 424.55**

Lipid peroxidation markers (RBCs)

 MDA (nM/gP) (RBCs)

12.80 ± 3.42

18.01 ± 5.16**

 Conjugated diene (nM hydroperoxides / gP) (RBCs)

111.10 ± 53.46

155.99 ± 80.07**

  1. Data are presented as mean ± SD. Inflammatory markers (TNF-α, IL-6), anti-oxidative parameters (FRAP: ferric reducing ability of plasma
  2. THIOL SH Plasma protein thiols (-SH), GPX Glutathione peroxidase, SOD Superoxyde dismutases) and lipid peroxidation markers (Conjugated dienes and MDA: Malondialdehyde) levels are shown in the RBCs of controls and patients, HB hemoglobin
  3. Statistical analyses were performed with the Mann-Whitney test. Significant differences between controls and CAD patients were observed as follows; *: p < 0.05; **: p < 0.001. Two independent experiments conducted in triplicate for each CAD patients and controls were realized