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Table 1 Clinical and laboratory characteristics in 41 subjects with Type 2 diabetes mellitus (T2DM) and in 36 subjects without T2DM

From: Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation

 

T2DM subjects (n = 41)

Non-diabetic subjects (n = 36)

P-value

Age (years)

60 (55–67)

51 (45–61)

< 0.001

Gender (men/women)

(19/22)

(9/27)

0.082

Systolic blood pressure (mm Hg)

142 (133–158)

128 (115–141)

< 0.001

Diastolic blood pressure (mm Hg)

86 (81–90)

78 (72–90)

0.014

BMI (kg/m2)

27.4 (25.5–33.0)

24.6 (22.5–26.8)

0.001

Waist (cm)

99 (90–107)

84 (76–92)

< 0.001

Glucose (mmol/l)

8.4 (7.2–10.2)

5.6 (5.0–6.2)

< 0.001

HbA1c (mmol/mol)

49 (43–58)

33 (30–37)

< 0.001

hsCRP (mg/l)

1.63 (1.03–2.87)

0.90 (0.42–2.42)

0.031

NEFA (mmol/l)

0.37 (0.29–0.45)

0.29 (0.21–0.35)

0.001

Total cholesterol (mmol/l)

5.53 (4.93–6.07)

5.46 (5.0–6.3)

0.80

Non-HDL cholesterol (mmol/l)

4.14 (3.50–4.86)

3.94 (3.39–4.53)

0.35

LDL cholesterol (mmol/l)

3.50 (2.63–3.93)

3.21 (2.78–3.84)

0.95

HDL cholesterol (mmol/l)

1.21 (1.01–1.60)

1.55 (1.32–1.82)

0.003

Triglycerides (mmol/l)

1.64 (1.21–2.16)

1.16 (0.90–1.76)

0.011

ApoB (g/l)

0.97 (0.81–1.11)

0.86 (0.73–0.96)

0.17

Apo A-1 (g/l)

1.30 (1/18–1.56)

1.46 (1.35–1.60)

0.076

ANGPTL4 (ng/ml)

5.68 (4.30–7.91)

3.42 (2.81–4.80)

< 0.001

PLTP (AU)

104.1 (98.5–113.6)

95.2 (83.4–100.0)

< 0.001

  1. Data are medians (interquartile range). Differences between subjects with and without T2DM were determined by Mann-Whitney U tests and Chi-square tests where appropriate. Apo: apolipoprotein; ANGPTL4: Angiopoietin-like 4; BMI: body mass index; HbA1c: glycated hemoglobin; HDL: high density lipoproteins; hsCRP: high sensitivity C-reactive protein; LDL: low density lipoproteins; NEFA: non-esterified fatty acids; PLTP: phospholipid transfer protein; LDL cholesterol was calculated in 39 T2DM subjects and in 35 non-diabetic subjects