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Table 1 Baseline characteristics of all obese with relative GHD children

From: Effects of recombinant human growth hormone administration on cardiovascular risk factors in obese children with relative growth hormone deficiency

Variable

rhGH group (n = 23)

Control group (n = 20)

P value

Age (yr)

11.61(1.73)

11.25(1.86)

0.516

Male/Female (n)

21/2

19/1

0.635

Prepuberty/Puberty, (n)

16/7

14/6

0.975

BMI SDS

2.64(0.74)

2.73(0.71)

0.676

BA-CA(yr)

1.43(1.88)

1.32(1.63)

0.826

Peak stimulated GH(μg/L)

1.8(1.2-3.7)

1.75(1.23-3.35)

0.761▲

IGF-1(ng/ml)

241.47(105.98)

291.1(151.95)

0.321#

TC(mmol/L)

4.81(0.65)

4.34(1.05)

0.093

HDL-C (mmol/L)

1.32(0.39)

1.22(0.22)

0.405#

LDL-C (mmol/L)

2.87(0.47)

2.58(0.85)

0.084#

TG(mmol/L)

1.49(0.76)

1.22(0.38)

0.326#

ALT(U/L)

22(15-64)

23(16.25-68.75)

0.567▲

AST(U/L)

25(22-32)

26.5(20.25-46.25)

1▲

Insulin(uIU/mL)

28.32(17.23)

27.92(16.73)

0.807#

FBG(mmol/L)

5.21(0.43)

5.12(0.43)

0.527▲

HOMA-IR

6.63(4.35)

6.38(3.92)

0.746#

HbA1c (%)

5.7(5.4-5.9)

5,6(5.325-5.875)

0.448

  1. BMI SDS body mass index standard deviation scores, BA–CA Bone age –chronological age, GH growth hormone, IGF-1 Insulin-like growth factor 1, TC total cholesterol, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, TG triglycerides, ALT alanine aminotransferase, AST aspartate aminotransferase, FBG fasting blood glucose, HOMA-IR homeostasis model assessment of IR, HbA1c Glycosylated haemoglobin
  2. #P value reported for log transformed values, but values in the table represent a back transformation to the original
  3. ▲Mann-Whitney U test or chi square test