Effects of apoC1 genotypes on the hormonal levels, metabolic profile and PAF-AH activity in Chinese women with polycystic ovary syndrome

Table 2 Hormonal levels, metabolic profile and PAF-AH activity in PCOS patients and controls

	Controls (n = 506)	PCOS (n = 575)	P	P ^a
Age (years)	27.96 ± 4.19	24.66 ± 3.96	< 0.001
BMI (kg/m²)	21.10 ± 2.91	23.10 ± 4.26	< 0.001
Hormonal levels
E₂ (pmol/L)	333.95 ± 351.36	284.06 ± 271.26	0.014	0.373
TT (nmol/L)	1.54 ± 0.54	2.42 ± 0.77	< 0.001	< 0.001
LH (IU/L)	8.72 ± 11.33	13.89 ± 10.91	< 0.001	< 0.001
FSH (IU/L)	6.67 ± 2.98	5.99 ± 2.23	< 0.001	0.015
LH/FSH	1.30 ± 1.32	2.35 ± 1.26	< 0.001	< 0.001
Metabolic profile
Fasting Ins (pmol/L)	66.98 ± 36.74	106.08 ± 74.24	< 0.001	< 0.001
Fasting Glu (mmol/L)	5.30 ± 0.73	5.37 ± 0.77	0.110	0.515
HOMA-IR	2.34 ± 1.90	3.79 ± 3.19	< 0.001	0.006
TG (mmol/L)	1.04 ± 0.90	1.42 ± 1.36	< 0.001	< 0.001
TC (mmol/L)	4.25 ± 0.70	4.41 ± 0.81	< 0.001	< 0.001
HDL-C (mmol/L)	1.51 ± 0.32	1.38 ± 0.35	< 0.001	0.006
LDL-C (mmol/L)	2.35 ± 0.61	2.55 ± 0.76	< 0.001	< 0.001
non-HDL-C (mmol/L)	2.73 ± 0.64	3.02 ± 0.81	< 0.001	< 0.001
AI	1.90 ± 0.68	2.37 ± 1.02	< 0.001	< 0.001
ApoA1 (g/L)	1.45 ± 0.21	1.42 ± 0.21	0.005	0.725
ApoB (g/L)	0.75 ± 0.17	0.82 ± 0.20	< 0.001	< 0.001
ApoB/apoA1	0.53 ± 0.14	0.60 ± 0.18	< 0.001	< 0.001
PAF-AH activity^a
Plasma PAF-AH (nmol/min/ml)	48.39 ± 10.81	47.44 ± 12.94	0.344	0.722
H-PAF-AH (nmol/min/ml)	5.14 ± 1.51	4.67 ± 1.91	0.001	0.031
ApoB-PAF-AH (nmol/min/ml)	43.25 ± 9.96	42.77 ± 11.89	0.604	0.967
ApoB-PAF-AH/H-PAF-AH	8.86 ± 2.48	10.04 ± 3.89	< 0.001	< 0.001

Values are presented as the mean ± SD
P^a All comparisons of parameters were corrected for differences in age and BMI between the two groups except the parameters of age and BMI
^a Control (n = 277), PCOS (n = 281)

ISSN: 1476-511X