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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α

Fig. 3

a and b Effect of apigetrin on gene expression of PPARγ, CEBP-α, SREBP-1c and FAS. c Effect of Ap7G on TNF-α and IL-6 gene expression 3T3-L1 cells were cultured 8 days after initiation of differentiation. Cells were treated with 0–100 μmol/L of Ap7G or for 8 days at 37 °C in a humidified 5% CO2 incubator. The relative expression level of PPARγ, CEBP-α, SREBP-1c, FAS, TNF-α and IL-6 was quantified by qRT-PCR. Final concentration of ethanol was 0.1%. Data were presented as means ± S.D. (n = 3). The asterisks (**) indicate a significant difference between control group and MDI-treated group (p < 0.01)

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