Myrtle berries seeds aqueous extract abrogates chronic alcohol consumption-induced erythrocytes osmotic stability disturbance, haematological and biochemical toxicity

Table 3 Effect of myrtle berries seeds aqueous extract (MBSAE) on chronic EtOH-induced erythrocytes oxidative stress

Treatment	MDA	SOD	CAT	GPx	-SH groups	GSH
Control	10.23 ± 1.12	37.93 ± 3.65	44.47 ± 4.42	26.48 ± 2.57	166.73 ± 9.84	44.84 ± 4.66
EtOH	28.06 ± 2.59*	22.16 ± 2.09*	26.28 ± 2.08*	14.31 ± 1.65*	73.66 ± 6.53*	19.69 ± 3.18*
EtOH + MBSAE-25	19.98 ± 1.31^#	29.38 ± 2.17^#	35.60 ± 2..56^#	19.81 ± 1.42^#	101.14 ± 6.33^#	28.78 ± 4.11^#
EtOH + MBSAE-50	14.47 ± 1.75^#	32.60 ± 2.229^#	38.73 ± 2.27^#	21.37 ± 0.72^#	122.47 ± 7.11^#	33.47 ± 3.18^#
EtOH + MBSAE-100	12.27 ± 1.44*	35.52 ± 2.83^#	41.72 ± 3.58^#	24.64 ± 1.81^#	147.18 ± 8.41^#	38.82 ± 3.64^#

Animals were daily treated with various doses of the MBSAE (25, 50 and 100 mg kg⁻¹, b.w., p.o.) or vehicle (NaCl 0.9%) before ethanol (30%, v/v, 10 mL kg^− 1, b.w.) intoxication during two months
MDA nmol of MDA/mg protein, SOD units/mg protein, CAT μmol of H₂O₂ consumed/min/mg protein, GPx nmol GSH oxidized/min/mg protein, -SH groups μmol/mg protein, GSH nmol of GSH/mg protein
The data are expressed as mean ± S.E.M. (n = 10), *: p < 0.05 compared to control group and #: p < 0.05 compared to EtOH group

ISSN: 1476-511X