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Table 5 Effect of HFD and GSSE on Copper; Lead; tyrosinase activity and glutamine synthetase activity

From: Protective effect of grape seed and skin extract against high-fat diet-induced dyshomeostasis of energetic metabolism in rat lung

 

SD

GSSE

HFD

HFD + GSSE

Cu2+ (mg/L)

286 ± 22.72

359.4 ± 33.32

216.5 ± 10.45*

308.2 ± 13.6§

Pb (μg/ L)

1673 ± 266.8

1637 ± 234.4

813.7 ± 152.2*

1575 ± 173§

Tyrosinase activity (U/ mg protein)

0.1383 ± 0.01239

0.1423 ± 0.006984

0.09833 ± 0.007356*

0.1393 ± 0.005783

Glutamine synthetase activity (nmol/min/mg protein)

1.947 ± 0.04842

1.913 ± 0.1618

1.353 ± 0.1179*

1.667 ± 0.1168§

  1. Results are expressed as mean ± SEM (N = 6). p < 0.05 was considered significant: (*) for HFD vs. SD, and (§) for HFD + GSSE vs. HFD. (**) and (§§) for p < 0.01