Association of the APOA1 rs964184 SNP and serum lipid traits in the Chinese Maonan and Han populations

Table 4 Comparison of the genotypes and serum lipid levels between males and females in the Maonan and Han populations

Ethnic/Genotype	n	TC (mmol/L)	TG (mmol/L)	HDL-C (mmol/L)	LDL-C (mmol/L)	ApoA1 (g/L)	ApoB (g/L)	ApoA1/ApoB
Maonan/Male
CC	230	4.92 ± 0.07	1.26(0.87)	1.59 ± 0.03	2.76 ± 0.06	1.40 ± 0.04	0.87 ± 0.02	1.69 ± 0.06
CG/GG	99	4.85 ± 0.11	1.43(1.44)	1.45 ± 0.05	2.69 ± 0.09	1.33 ± 0.05	0.89 ± 0.02	1.54 ± 0.09
F		0.247	−0.837	6.996	0.317	1.452	0.412	1.784
P		0.620	0.403	0.009	0.574	0.230	0.521	0.183
Maonan/Female
CC	366	5.06 ± 0.08	1.19(0.68)	1.69 ± 0.02	2.91 ± 0.05	1.41 ± 0.01	0.88 ± 0.01	1.67 ± 0.03
CG/GG	172	4.93 ± 0.11	1.31(0.88)	1.61 ± 0.04	2.84 ± 0.08	1.38 ± 0.02	0.86 ± 0.02	1.67 ± 0.05
F		1.001	−1.361	3.903	0.676	1.025	0.316	0.000
P		0.318	0.174	0.049	0.412	0.312	0.574	0.998
Han/Male
CC	206	5.12 ± 0.11	1.11(0.95)	1.66 ± 0.04	2.92 ± 0.09	1.34 ± 0.03	0.89 ± 0.02	1.57 ± 0.05
CG/GG	100	4.98 ± 0.16	1.34(2.26)	1.52 ± 0.06	2.88 ± 0.13	1.23 ± 0.04	0.94 ± 0.03	1.38 ± 0.07
F		0.519	−1.140	3.669	0.077	5.286	1.359	5.272
P		0.473	0.254	0.058	0.782	0.023	0.246	0.024
Han/Female
CC	317	4.87 ± 0.10	0.97(0.82)	1.74 ± 0.04	2.88 ± 0.08	1.30 ± 0.02	0.82 ± 0.02	1.67 ± 0.05
CG/GG	197	4.97 ± 0.14	1.15(0.83)	1.72 ± 0.05	2.83 ± 0.12	1.31 ± 0.03	0.82 ± 0.03	1.69 ± 0.07
F		0.328	−1.902	0.127	0.128	0.096	0.015	0.032
P		0.567	0.057	0.722	0.721	0.758	0.901	0.858

TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B. The value of triglyceride was presented as median (interquartile range), the difference among the genotypes was determined by the Wilcoxon-Mann-Whitney test

ISSN: 1476-511X