Association of the APOA1 rs964184 SNP and serum lipid traits in the Chinese Maonan and Han populations

Qiu, Ling; Yin, Rui-Xing; Khounphinith, Eksavang; Zhang, Fen-Han; Yang, De-Zhai; Pan, Shang-Ling

doi:10.1186/s12944-018-0759-8

Lipids in Health and Disease

Table 5 Relationship between serum lipid parameters and relative factors in the Maonan and Han populations

From: Association of the APOA1 rs964184 SNP and serum lipid traits in the Chinese Maonan and Han populations

Lipid	Risk factor	B	Std. error	Beta	t	P
Maonan and Han
TC	Age	0.010	0.003	0.146	3.679	0.000
	Height	−0.014	0.007	−0.124	−2.033	0.042
	Waist circumference	0.024	0.006	0.204	3.911	0.000
TG	Alcohol consumption	0.006	0.002	0.114	3.063	0.002
	Height	−0.025	0.010	− 0.149	−2.506	0.012
	Weight	0.047	0.018	0.300	2.581	0.010
	Waist circumference	0.039	0.009	0.223	4.396	0.000
HDL-C	Gender	0.161	0.039	0.191	4.162	0.000
	Alcohol consumption	0.002	0.000	0.183	4.935	0.000
	Waist circumference	−0.009	0.002	− 0.212	−4.198	0.000
	Pulse pressure	−0.002	0.001	−0.074	−2.043	0.041
	Ethnic group	0.070	0.028	0.082	2.497	0.013
	Genotype	−0.051	0.014	−0.115	−3.591	0.000
LDL-C	Age	0.009	0.002	0.168	4.305	0.000
	Alcohol consumption	−0.003	0.001	−0.120	− 3.163	0.001
	Waist circumference	0.019	0.005	0.211	4.135	0.000
ApoA1	Gender	0.089	0.030	0.143	3.025	0.003
	Cigarette smoking	0.004	0.002	0.103	2.558	0.011
	Alcohol consumption	0.002	0.000	0.174	4.569	0.000
	Waist circumference	−0.004	0.002	−0.108	−2.083	0.038
	Ethnic group	−0.091	0.022	−0.141	−4.204	0.000
	Genotype	−0.023	0.011	−0.069	−2.103	0.036
ApoB	Age	0.002	0.000	0.148	3.878	0.000
	Height	−0.003	0.001	−0.130	−2.234	0.026
	Waist circumference	0.007	0.001	0.330	6.614	0.000
ApoA1/ApoB	Gender	0.177	0.054	0.148	3.273	0.001
	Age	−0.004	0.001	− 0.114	−2.977	0.003
	Cigarette smoking	0.008	0.003	0.103	2.661	0.008
	Alcohol consumption	0.003	0.001	0.176	4.801	0.000
	Waist circumference	−0.018	0.003	−0.288	−5.773	0.000
	Ethnic group	−0.086	0.040	−0.070	−2.162	0.031
Maonan
TC	Age	0.009	0.004	0.127	2.621	0.009
	Gender	0.276	0.129	0.124	2.138	0.033
	Waist circumference	0.024	0.007	0.218	3.389	0.001
TG	Height	−0.023	0.011	−0.134	−2.006	0.045
	Weight	0.045	0.021	0.287	2.119	0.035
	Alcohol consumption	0.008	0.002	0.170	3.574	0.000
	Waist circumference	0.038	0.011	0.217	3.471	0.001
HDL-C	Gender	0.166	0.046	0.200	3.623	0.000
	Alcohol consumption	0.002	0.001	0.209	4.470	0.000
	Waist circumference	−0.010	0.003	−0.235	−3.825	0.000
	Pulse pressure	− 0.002	0.001	− 0.096	−2.129	0.034
	Genotype	−0.055	0.017	−0.124	−3.179	0.002
LDL-C	Age	0.008	0.003	0.148	3.161	0.002
	Alcohol consumption	−0.004	0.001	−0.183	− 3.858	0.000
	Waist circumference	0.021	0.005	0.247	3.969	0.000
ApoA1	Gender	0.092	0.039	0.138	2.392	0.017
	Alcohol consumption	0.001	0.000	0.149	3.051	0.002
	Waist circumference	−0.005	0.002	−0.137	−2.131	0.034
ApoB	Age	0.002	0.001	0.159	3.470	0.001
ApoB	Waist circumference	0.008	0.001	0.376	6.176	0.000
ApoA1/ApoB	Age	−0.005	0.002	−0.131	−2.852	0.005
	Alcohol consumption	0.003	0.001	0.183	3.955	0.000
	Waist circumference	−0.020	0.004	−0.325	−5.336	0.000
Han
TC	Age	0.010	0.005	0.147	2.133	0.034
TC	Diastolic blood pressure	0.014	0.005	0.162	2.670	0.008
TG	Cigarette smoking	0.035	0.012	0.202	3.056	0.002
	Waist circumference	0.043	0.016	0.245	2.696	0.007
	Diastolic blood pressure	0.015	0.007	0.129	2.207	0.028
	Genotype	0.248	0.083	0.164	2.993	0.003
HDL-C	Gender	0.166	0.074	0.193	2.247	0.025
HDL-C	Alcohol consumption	0.002	0.001	0.152	2.426	0.016
LDL-C	Age	0.010	0.004	0.170	2.457	0.015
LDL-C	Cigarette smoking	−0.018	0.008	−0.163	−2.384	0.018
ApoA1	Gender	0.097	0.045	0.187	2.172	0.031
	Alcohol consumption	0.002	0.001	0.263	4.190	0.000
	Cigarette smoking	0.006	0.002	0.173	2.497	0.013
ApoB	Gender	−0.099	0.034	−0.236	−2.881	0.004
ApoB	Waist circumference	0.006	0.002	0.226	2.476	0.014
ApoA1 /ApoB	Gender	0.358	0.087	0.343	4.123	0.000
	Cigarette smoking	0.011	0.004	0.171	2.550	0.011
	Alcohol consumption	0.003	0.001	0.161	2.648	0.009

TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B, B unstandardized coefficient, Beta standardized coefficient

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ISSN: 1476-511X

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