Table 1 Baseline Characteristics of participants
TG/HDL-C | Q1 | Q2 | Q3 | Q4 | P-value | P-value* |
|---|---|---|---|---|---|---|
Number | 228 | 228 | 228 | 228 | ||
AGE (years, mean ± sd) | 50.8 ± 10.0 | 51.8 ± 9.7 | 51.2 ± 9.0 | 50.7 ± 9.6 | 0.638 | 0.600 |
BMI (kg/m2, mean ± sd) | 21.5 ± 2.4 | 22.6 ± 2.8 | 23.6 ± 3.4 | 24.7 ± 2.9 | < 0.001 | < 0.001 |
SBP (mmHg, mean ± sd) | 114.1 ± 13.4 | 118.5 ± 15.0 | 123.4 ± 15.1 | 124.9 ± 14.0 | < 0.001 | < 0.001 |
DBP (mmHg, mean ± sd) | 71.4 ± 9.1 | 74.9 ± 9.8 | 78.3 ± 10.2 | 80.0 ± 8.7 | < 0.001 | < 0.001 |
AST(IU/L, mean ± sd) | 19.3 ± 6.2 | 19.8 ± 6.0 | 20.9 ± 9.4 | 23.4 ± 9.5 | < 0.001 | < 0.001 |
ALT(IU/L, mean ± sd) | 16.0 (12.0–20.0) | 17.0 (13.0–23.0) | 20.0 (15.0–28.0) | 24.0 (18.0–35.0) | < 0.001 | < 0.001 |
GGT (IU/L, mean ± sd) | 14.0(11.0–17.0) | 18.0(14.0–25.2) | 20.0(15.0–33.0) | 24.0 (19.0–41.0) | < 0.001 | < 0.001 |
Uric acid (mg/dl, mean ± sd) | 4.5 ± 1.2 | 4.9 ± 1.3 | 5.5 ± 1.2 | 6.1 ± 1.2 | < 0.001 | < 0.001 |
Fasting glucose (mg/dL, mean ± sd) | 93.1 ± 8.3 | 96.2 ± 10.7 | 100.8 ± 20.1 | 102.1 ± 12.4 | < 0.001 | < 0.001 |
TC (mg/dL, mean ± sd) | 202.7 ± 34.6 | 205.8 ± 34.4 | 210.3 ± 34.7 | 220.6 ± 37.7 | < 0.001 | < 0.001 |
LDL (mg/dL, mean ± sd) | 115.2 ± 29.2 | 126.7 ± 29.0 | 133.7 ± 29.7 | 136.6 ± 34.4 | < 0.001 | < 0.001 |
eGFR(mL/min/1.73 m2, mean ± sd) | 73.9 ± 13.2 | 70.8 ± 12.2 | 69.1 ± 10.7 | 67.8 ± 11.1 | < 0.001 | < 0.001 |
baPWV (cm/s, mean ± sd) | 1344.9 ± 220.6 | 1410.0 ± 231.8 | 1435.0 ± 232.1 | 1473.2 ± 279.9 | < 0.001 | < 0.001 |
SEX (n,%) | < 0.001 | – | ||||
Male | 76 (33.3%) | 141 (61.8%) | 173 (75.9%) | 202 (88.6%) | ||
Female | 152 (66.7%) | 87 (38.2%) | 55 (24.1%) | 26 (11.4%) | ||
Current smokig (n,%) | < 0.001 | – | ||||
None | 209 (91.7%) | 181 (79.4%) | 166 (72.8%) | 159 (69.7%) | ||
Current | 19 (8.3%) | 47 (20.6%) | 62 (27.2%) | 69 (30.3%) | ||
Ex-Smoking (n,%) | < 0.001 | – | ||||
No | 162 (71.1%) | 126 (55.3%) | 91 (39.9%) | 82 (36.0%) | ||
Yes | 66 (28.9%) | 102 (44.7%) | 137 (60.1%) | 146 (64.0%) | ||
Regular Exercise (> 1 week) (n,%) | 0.003 | – | ||||
No | 165 (74.3%) | 172 (76.8%) | 187 (82.7%) | 195 (87.1%) | ||
Yes | 57 (25.7%) | 52 (23.2%) | 39 (17.3%) | 29 (12.9%) | ||
Fatty liver (n,%) | < 0.001 | – | ||||
None | 210 (92.1%) | 193 (84.6%) | 141 (62.1%) | 102 (44.7%) | ||
Yes | 18 (7.9%) | 35 (15.4%) | 86 (37.9%) | 126 (55.3%) | ||
Post-Menopausal (n,%) | 0.118 | – | ||||
No | 75 (49.3%) | 33 (37.9%) | 18 (32.7%) | 12 (46.2%) | ||
Yes | 77 (50.7%) | 54 (62.1%) | 37 (67.3%) | 14 (53.8%) | ||
Alcohol consumption (n,%) | < 0.001 | – | ||||
< 40 (g/week) | 174 (76.3%) | 140 (62.2%) | 131 (58.2%) | 136 (61.5%) | ||
≤40–140 | 27 (11.8%) | 48 (21.3%) | 36 (16.0%) | 39 (17.6%) | ||
> 140–280 | 18 (7.9%) | 21 (9.3%) | 27 (12.0%) | 22 (10.0%) | ||
> 280 | 9 (3.9%) | 16 (7.1%) | 31 (13.8%) | 24 (10.9%) | ||
ABI | 1.3 ± 0.8 | 1.2 ± 0.1 | 1.2 ± 0.1 | 1.2 ± 0.1 | < 0.001 |