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Table 1 Clinical characteristics of control group and the extent of coronary artery disease patients

From: Peripheral-blood gene expression profiling studies for coronary artery disease and its severity in Xinjiang population in China

 

Control group

(N = 9)

Mild stenosis group

(N = 6)

Moderate stenosis group

(N = 6)

Severe stenosis group

(N = 9)

P Value

Age ± sd (years)

43.66 ± 5.61

50.36 ± 4.31

52.66 ± 5.19

50.16 ± 5.36

0.772

BMI ± sd (kg/m2)

23.20 ± 2.52

25.20 ± 2.52

26.50 ± 1.92

28.13 ± 3.36

0.640

Hx of Hyperlipidemia (n, %)

0

2 (33%)

4 (66%)

6 (66%)

0.541

Hx of Hypertension (n, %)

0

2 (33%)

3 (50%)

4 (44%)

0.813

Hx of Diabetes (n, %)

0

0

0

0

 

Hx of Smoking (n, %)

2 (22%)

3 (50%)

3 (50%)

8 (88%)

0.750

Coronary arterial stenosis (n, %)

0

39 ± 4%

67 ± 5%

81 ± 6%

<0.001

LV ejection fraction (%)

50.7 ± 1%

55.76 ± 2%

59.16 ± 2%

62.1 ± 4%

0.780

Biometrics

 Systolic blood pressure ± sd (mmHg)

118.88 ± 6.00

120.38 ± 9.39

122.33 ± 6.00

138.4 ± 8.93

0.813

 Diastolic blood pressure ± sd (mmHg)

75.55 ± 7.26

71 ± 3.22

77.44 ± 8.09

87.9 ± 4.22

0.731

Laboratory parameterst

 Total cholesterol ± sd (mmol/L)

3.67 ± 0.34

3.77 ± 0.45

3.99 ± 0.34

4.2 ± 1.19

0.042

 LDL-cholesterol ± sd (mmol/L)

2.19 ± 0.38

2.91 ± 0.58

2.98 ± 0.71

3.25 ± 0.77

0.087

 HDL-cholesterol ± sd (mmol/L)

1.94 ± 0.91

1.11 ± 0.25

1.24 ± 0.21

1.09 ± 0.45

0.083

 Triglycerides (mmol/L)

1.03 ± 0.45

1.64 ± 0.45

2.64 ± 0.45

3.07 ± 0.85

0.032

 Apolipoprotein A (g/L)

1.16 ± 0.06

1.61 ± 0.06

1.96 ± 0.06

2.15 ± 0.31

1

 Apolipoprotein B (g/L)

0.76 ± 0.06

1.09 ± 0.06

1.29 ± 0.08

1.99 ± 0.25

1

 HbAIC (%)

4.45 ± 0.46

5.65 ± 0.36

5.97 ± 0.46

6.01 ± 0.87

0.431

 Hs-CRP (mg/L)

4.34 ± 0.14

3.506 ± 0.14

3.906 ± 0.14

4.106 ± 1.00

0.866

 Hematocrit (HCT)

4.13 ± 0.23

4.31 ± 0.13

4.33 ± 0.32

4.79 ± 0.15

0.753

 Creatinine (mg/dL) (%)

73.13 ± 11.17

76.13 ± 10.17

78.13 ± 13.17

76.34 ± 12.25

0.201

 White blood cell count (109/L)

6.12 ± 1.12

6.92 ± 1.21

7.12 ± 1.32

8.02 ± 2.26

0.567

Medications

 Statins (n, %)

0

3 (50%)

4 (66%)

7 (77%)

0.850