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Table 2 12 differentially expressed genes associated with toll-like receptor signaling pathway in the extent of coronary artery stenosis patients

From: Peripheral-blood gene expression profiling studies for coronary artery disease and its severity in Xinjiang population in China

Gene symbol

Gene description

Trend 1

Trend 2

Trend 3

p-value

MAPK3

Mitogen-activated protein kinase 3

0.1681

0.3593

0.9498

0.00045

MAPK1

Mitogen-activated protein kinase 1

0.2921

0.5725

1.1005

0.00196

CHUK

Conserved helix-loop-helix ubiquitous kinase

0.1854

0.2862

0.6197

0.00622

PIK3CB

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

0.4401

0.4743

1.1232

0.00830

MAPK14

Mitogen-activated protein kinase 14

0.3399

0.7724

1.9161

0.00960

TLR4

Toll like receptor 4

0.6287

0.8780

1.9592

0.01065

IFNAR1

Interferon alpha and beta receptor subunit 1

0.3049

0.9418

1.0834

0.01283

MAPK13

Mitogen-activated protein kinase 13

0.1807

0.3373

0.7193

0.02156

JUN

Jun proto-oncogene

0.3740

0.4746

1.0779

0.02579

TLR2

Toll like receptor 2

0.2299

0.4885

1.2470

0.03053

MYD88

Myeloid differentiation primary response 88

0.4350

0.6164

0.8260

0.03805

IRAK4

Interleukin 1 receptor associated kinase 4

0.0101

0.3213

0.7935

0.04165

  1. Trend 1: Mid CAD compared with control group; Trend 2: Moderate CAD compared with mid group; Trend 3: Severe CAD compared with moderate group
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Lipids in Health and Disease

ISSN: 1476-511X