Fig. 1

Full-model linear regression analysis of various lipid parameters (as independent variables) and target organ damage: Linear regressions were performed to investigate the association of: (I) pulse wave velocity (PWV), (II) ankle-brachial index (ABI) and (III) estimated glomerular filtration rate (eGFR) with one-SD increment of various lipid parameters respectively. The potential confounders including age, gender, smoke, BMI, fasting blood glucose, systolic blood pressure and lipid lowering therapy, together with lipid parameters, were forced into respective models. Dark color was used to highlight the coefficients achieving statistical significance, and while color represented the coefficients not achieving statistical significance. Only four combined lipid parameters significantly associated with all target organ damage. TC: total cholesterol. TG: triglycerides. HDL: high density lipoprotein. LDL: low density lipoprotein