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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

Fig. 5

Effect on toll-like receptor (TLRs) signaling pathways in plasma of total mRNAs obtained from δ-tocotrienol treatment of hepatitis C patients. The TLRs were down-regulated by δ-tocotrienol treatment, these belong to the family of pathogen-associated receptors, and bind to a number of bacteria and viruses, such as viral DNA, lipopolysaccharide, and CpG DNA motifs. TLRs form a complex with different combinations of adapter molecules like MYD88, TRAF6 and TIRAP to initiate signal transduction upon ligand binding

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Lipids in Health and Disease

ISSN: 1476-511X