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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

Fig. 7

Effect on nuclear factor kappaB (NF-κB) in plasma of total mRNAs obtained from δ-tocotrienol treatment of hepatitis C patients. δ-Tocotrienol modulates NF-κB transcription factors, which are key regulators of gene expression and act in response to stress and the development of innate and acquired immunity. A number of NF-κB activators mediate the site-specific phosphorylation of serine on IκB (inhibitor of NF-κB), there by marking IκB for ubiquitination and subsequent proteasomal destruction

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Lipids in Health and Disease

ISSN: 1476-511X