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Fig. 8 | Lipids in Health and Disease

Fig. 8

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

Fig. 8

Effect on nitric oxide synthase (iNOS) in plasma of total mRNAs obtained from δ-tocotrienol treatment of hepatitis C patients. The iNOS was down-regulate by δ-tocotrienol treatment. It produces nitric oxide from L-arginine, a cytotoxic weapon generated by macrophages. The catalytic activity of iNOS is to kill or inhibit the growth of invading microorganisms. Nitric oxide is a free radical effector of the innate immune system that inhibits pathogen replication. A variety of extracellular stimuli (components of bacteria and fungi) can activate signaling pathways that help to initiate expression of iNOS

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Lipids in Health and Disease

ISSN: 1476-511X