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Table 1 Estimation of basic RNA-sequence expresion unit (FPKM) of δ-tocotrienol treated hepatitis C patients1

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

#

RNA-Seq expression unit

Number of genes

Genes based on 2-fold

Genes based on 4-fold

Genes based on 8-fold

1

FPKM > 1

12614

9480

5369

2136

2

FPKM > 2

7426

1366

696

527

3

FPKM > 5

3323

379

285

268

  1. 1The gene expression level and fold change (post-dose vs pre-dose) of FPKM were calculated at more than 1, 2, or 5 at 2-fold, 4-fold, and 8-fold after filtering million-fold up-regulation and down-regulation. The RNA-seq analyses data based on FPKM >1 and 8-fold change of 2136 genes (0 values were replaced with 0.001) of ratios of post-dose over pre-dose treatment of δ-tocotrienol to hepatitis C patients was submitted into “Ingenuity Pathway Analyses (IPA)” for core analysis (Ingenuity Systems, Redwood City, CA)