Fig. 5

(a) Expression of cell survival signaling proteins in the brain of STZ-induced type 2 DM animals. Proteins studies by Western blot include: (pAkt/tAkt), # P < 0.001 vs untreated control; (pmTOR/mTOR) §P ≤ 0.01 vs untreated control. (pPi3K/PI3K) # P ≤ 0.01 vs untreated control along with beta Actin. All values are expressed as mean ± SEM. (b) Plasma BDNF/TNF-α/IL-6 levels. All values are expressed as mean ± SEM. §P ≤ 0.05 compared to respective control ^₰P ≤ 0.01 compared to control. ^*P ≤ 0.05 compared to control. (c) Plasma LXA4 levels in STZ-induced type 2 DM animals compared to control. Data are mean ± SEM. §P ≤ 0.01 compared to control