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Table 1 Concentrations of various anti-oxidants, lipid peroxides and nitric oxide in pancreatic tissue in vivo

From: Dysregulation of PI3K-Akt-mTOR pathway in brain of streptozotocin-induced type 2 diabetes mellitus in Wistar rats

Summary of the analysis of various anti-oxidant/lipid peroxides and nitric oxide levels in pancreas of stz treated diabetic rats
Tissue Group SOD (Units/mg protein) CAT (mM H2O2/min/mg protein GST (mM/min/gm protein) GPX (mM/min/gm protein) LPO
(μM TMOP)
Nitric oxide
(μM nitrite)
Pancreas
[in vivo)
Control 36.9 ± 1.9 911 ± 62.8 19.58 ± 0.40 116.5 ± 2.6 1.3 ± 0.05 1.1 ± 0.02
STZ [65 mg/kg) 74.4 ± 3.2* 1494 ± 41* 54.8 ± 0.36* 191 ± 3.9* 1.5 ± 0.1* 1.6 ± 0.8*
  1. Superoxide dismutase (SOD) is expressed as U SOD/mg of protein; Catalase (CAT) is expressed as μM of H2O2 consumed/minute/mg of protein; Glutathione-S-transferase (GST) is expressed as μM conjugate formed/ minute/gm of protein; Glutathione peroxidase (GPX) is expressed as μg of glutathione consumed/minute/gm of protein. Lipid peroxides formed are expressed as μmoles of TMOP formed; Nitric oxide formed is expressed *P < 0.05, vs untreated control Vs respective STZ-treated group. All the above set of experiments done on n = 8 animal experiment in vivo. All values expressed as mean ± SEM