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Table 1 Baseline characteristics between incident cases of T2DM and control subjects

From: Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study

Phenotypes

Cases (n = 538)

Controls (n = 538)

χ2/Z value

P value

Sex (male)

195 (36.25)

195 (36.25)

0.00

Matching value

Age (years)

59.0 (51.0–66.0)

59.0 (51.0–66.0)

0.02

Matching value

BMI (kg/m2)

26.39 (23.78–28.77)

24.18 (22.02–26.57)

8.51

<  0.0001

Waist-height ratio

0.56 (0.52–0.61)

0.52 (0.48–0.57)

8.91

<  0.0001

Smoking

 Yes

132 (24.54)

142 (26.39)

0.49

0.484

 No

406 (75.46)

396 (73.61)

  

Drinking

 Yes

68 (12.64)

49 (9.11)

3.46

0.063

 No

470 (87.36)

489 (90.89)

  

Physical activity

 Low

269 (50.00)

286 (53.16)

1.15

0.562

 Moderate

111 (20.63)

107 (19.89)

  

 High

158 (29.37)

145 (26.95)

  

Family history of diabetes

 Yes

45 (10.84)

25 (5.94)

6.55

0.010

 No

370 (89.16)

396 (94.06)

  

FPG (mmol/L)

5.98 (5.48–6.44)

5.31 (4.97–5.66)

14.70

<  0.001

SBP (mmHg)

130.83 (117.00–145.83)

122.33 (111.92–137.33)

5.44

<  0.001

DBP (mmHg)

82.33 (74.33–91.08)

78.33 (70.67–86.33)

5.31

<  0.001

TC (mmol/L)

4.65 (4.10–5.29)

4.46 (3.89–5.07)

3.65

<  0.001

TG (mmol/L)

1.85 (1.22–2.86)

1.44 (1.03–2.05)

7.07

<  0.001

HDL-C (mmol/L)

1.09 (0.95–1.24)

1.15 (1.00–1.32)

4.56

<  0.001

LDL-C (mmol/L)

2.7 (2.20–3.10)

2.60 (2.10–3.10)

1.11

0.268

  1. BMI body mass index, FPG fasting plasma glucose, TC total cholesterol, TG triglycerides, HDL-C high density lipoprotein, LDL-C low density lipoprotein
  2. Data are number (percentage) or median (interquartile range)
  3. P value for comparison between cases and controls
  4. Mann-Whitney U test or χ2 test were used to test differences between groups