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Table 1 Association analysis of the three VDR SNPs and cases (stage I)

From: Vitamin D receptor polymorphism rs2228570 is significantly associated with risk of dyslipidemia and serum LDL levels in Chinese Han population

SNP Group Genotype OR (95% CI)a Allele
   WT Ht+ MT Additive Dominant Recessive Major/Minor OR (95% CI) P -value
rs11574129   TT TC + CC     T/C   
  Control 1265 560 + 55 1.069 (0.923–1.238) 1.055 (0.89–1.25) 1.2 6 (0.809–1.964) 3090/670 1.07 (0.92–1.24) 0.46c
  case 578 265 + 32 P = 0.376 P = 0.536 P = 0.306 1421/329   0.38b
rs2228570   CC TC + TT     C/T   
  Control 539 939 + 401 1.255 (1.118–1.409) 1.384 (1.136–1.6) 1.356 (1.1–1.671) 2017/1741 1.25 (1.12-1.41) 0.832c
  case 308 422 + 146 P < 0.001 P =0.001 P = 0.004 1038/714   0.001b
rs739837   CC TC + TT     C/T   
  Control 991 749 + 139 1.094 (0.965–1.241) 1.108 (0.944–1.301) 1.157 (0.862–1.553) 2731/1027 1.09 (0.96–1.24) 0.877c
  case 439 362 + 74 P =0.161 P = 0.209 P = 0.33 1240/510   0.17b
  1. a Adjusted for sex and age
  2. b P-value of χ2 test for comparison of allele between case and control group
  3. c P-value of Fisher’s exact χ2 test for HWE
  4. WT wild type, Ht heterozygote, MT mutant type
  5. OR Odds ratio
  6. CI Confidence interval