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Table 2 Association analysis of the rs2228570 and cases (stage II)

From: Vitamin D receptor polymorphism rs2228570 is significantly associated with risk of dyslipidemia and serum LDL levels in Chinese Han population

SNP

Group

Genotype OR (95% CI)a

Allele

 

WT

Ht + MT

Additive

Dominant

Recessive

Major/Minor

OR (95% CI)

P-value

rs2228570

 

CC

TC + TT

   

C/T

  
 

Control

902

1558+661

1.146 (1.053–1,247)

1.184 (1.018–1.376)

1.209 (1.064–1.374)

3362/2880

1.15 (1.05-1.25)

0.806c

 

case

553

815 + 310

P = 0.002

P = 0.028

P = 0.004

1921/1435

 

0.002b

  1. a Adjusted for sex and age
  2. b P-value of χ2 test for comparison of allele between case and control group
  3. c P-value of Fisher’s exact χ2 test for HWE
  4. WT wild type, Ht heterozygote, MT mutant type
  5. OR Odds ratio
  6. CI Confidence interval