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Table 4 Threshold effect analysis of ApoE on EBB-induced bleeding using two-piecewise linear regression

From: Plasma apolipoprotein E level is associated with the risk of endobronchial biopsy-induced bleeding in patients with lung cancer

Inflection point of ApoE (mg/dL) Biopsy-induced Bleedinga
OR (95% CI) P value
Inflection point I
 < 3.5 1.00 (0.70, 1.42) 0.9942
 > 3.5 0.67 (0.47, 0.96) 0.0272
Inflection point II
 < 5.9 0.82 (0.69, 0.96) 0.0156
 > 5.9 1.49 (1.03, 2.16) 0.0329
  1. aAdjust for: Sex, Age, SBP, DBP, smoking, TC, triglyceride, HDLC, LDLC, location of lesion, histological types, stage, diabetes, hypertension, COPD, CHD, ALT, AST, and CRP
  2. Apo apolipoprotein, HDLC high density lipoprotein cholesterol, CRP C-reactive protein, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDLC low density lipoprotein cholesterol, COPD Chronic obstructive pulmonary disease, CHD coronary heart disease, ALT alanine aminotransferase, AST aspartate aminotransferase