Characteristics
|
Total
|
Women
|
Men
|
P Value*
|
---|
Number of subjects
|
1496
|
929
|
567
| |
---|
Age, years
|
55.7 ± 14.1
|
55.9 ± 14.1
|
55.3 ± 13.9
|
0.40
|
History of hypertension, %
|
30.3
|
31.8
|
28.0
|
0.12
|
Current smoker, %
|
20.6
|
1.9
|
51.1
|
< 0.001
|
BMI, kg/m2
|
22.5 ±2.9
|
22.5 ± 3.0
|
22.5 ± 2.8
|
0.85
|
Waist circumference, cm
|
72.2 ± 8.1
|
69.6 ± 7.1
|
76.8 ± 7.7
|
< 0.001
|
Waist/Hip
|
0.81± 0.07
|
0.78 ±0.06
|
0.85 ± 0.06
|
< 0.001
|
SBP, mmHg
|
132 ± 21
|
131 ± 21
|
134 ± 20
|
0.002
|
DBP, mmHg
|
77 ± 12
|
76 ± 12
|
79 ± 12
|
< 0.001
|
HbA1c, %
|
5.1 ± 0.4
|
5.1 ± 0.4
|
5.2 ± 0.4
|
< 0.001
|
Glucose, mmol/L
|
5.52 ± 0.70
|
5.52 ± 0.68
|
5.52 ± 0.74
|
0.93
|
IRI, U/mL
|
2.9 (1.7–5.5)
|
3.3 (1.9–5.6)
|
2.5 (1.3–4.8)
|
< 0.001
|
TC, mmol/L
|
5.16 ± 0.93
|
5.31 ± 0.93
|
4.92 ± 0.87
|
< 0.001
|
HDL-C, mmol/L
|
1.54 ± 0.38
|
1.58 ± 0.37
|
1.47 ± 0.37
|
< 0.001
|
Non-HDL-C, mmol/L
|
3.62 ± 0.38
|
3.73 ± 0.99
|
3.45 ± 0.94
|
< 0.001
|
TG, mmol/L
|
0.99 (0.71–1.42)
|
0.95 (0.68–1.33)
|
1.11 (0.78–1.61)
|
< 0.001
|
Phospholipids, mg/dL
|
220 ± 33
|
223 ± 32
|
214 ± 33
|
< 0.001
|
Free fatty acids, Eq/L
|
561 (265–854)
|
629 (292–912)
|
486 (231–755)
|
< 0.001
|
LCAT activity, nmol mL-1 hr-1
|
76.9 ± 21.4
|
75.6 ± 21.2
|
79.0 ± 21.5
|
0.003
|
- Values are expressed as means ± standard deviations except IRI, TG, and free fatty acids which are given as the medians and the interquartile ranges in parentheses
- *P < 0.05 is considered to indicate statistically significant differences between men and women. The Mann-Whitney nonparametric test was used for the differences of IRI, TG and free fatty acids. The other continuous variables were estimated by Student’s t-test
- BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycosylated hemoglobin A1c, IRI immunoreactive insulin, TC total cholesterol, HDL-C high-density lipoprotein-cholesterol, TG triglyceride, LCAT lecithin cholesterol acyltransferase