Table 2 Subgroup analyses stratified by various factors
Factors | Subgroups | Studies (n) | Patients(n) (Case/Control) | I2(%) | Heterogeneity (p) | SMD | 95% CI | Z test (p) |
|---|---|---|---|---|---|---|---|---|
Ethnicity | Caucasians | 7 | 398/315 | 77.7 | < 0.001 | 0.42 | 0.06–0.71 | 0.021 |
Asians | 6 | 356/186 | 0.0 | 0.661 | 0.19 | 0.01–0.18 | 0.037 | |
Joint involvement | Knee | 8 | 499/299 | 65.7 | 0.005 | 0.44 | 0.17–0.72 | 0.002 |
Hand | 4 | 185/132 | 20.1 | 0.289 | 0.18 | -0.07-0.44 | 0.161 | |
Knee and Hip | 1 | 70/70 | – | – | 0.00 | -0.33-0.34 | 0.980 | |
Stage | early OA | 2 | 77/66 | 0.0 | 0.533 | 0.00 | -0.57-0.58 | 0.356 |
Middle & late OA | 11 | 677/435 | 71.8 | < 0.001 | 0.23 | -0.17-0.63 | 0.004 |