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Table 2 Comparison of the anthropometric measurements and metabolic profile of lean and obese patients with polycystic ovary syndrome (POCS) and lean and obese controls

From: A study of ghrelin and leptin levels and their relationship to metabolic profiles in obese and lean Saudi women with polycystic ovary syndrome (PCOS)

Parameter Patient Group Mean SD p 1 Control Group Mean SD p 2 p 3
Age (years) Lean 26.05 0.63 0.131 Lean 23.95 0.60 0.231 0.018
Obese 27. 24 0.48 Obese 25.14 0.79 0.028
Body mass index (BMI) (kg/m2) Lean 22.86 0.20 0.0001 Lean 20.85 0. 24 < 0.0001 < 0.0001
Obese 33.64 0.62 Obese 34.47 0.72 0.387
Weight/height ratio Lean 0.79 0.01 0.0001 Lean 0.71 0.006 < 0.0001 < 0.0001
Obese 0.88 0.01 Obese 0.81 0.007 < 0.0001
Cholesterol (mmol/L) Lean 3.91 0.06 0.0001 Lean 3.42 0.05 < 0.0001 < 0.0001
Obese 4.68 0.11 Obese 3.86 0.07 < 0.0001
Triglyceride (mmol/L) Lean 0.93 0.05 0.0001 Lean 0.68 0.029 < 0.0001 < 0.0001
Obese 1.21 0.05 Obese 1.04 0.057 0.025
HDL-C (mmol/L) Lean 1.04 0.04 0.132 Lean 1.44 0.040 < 0.0001 < 0.0001
Obese 1.11 0.04 Obese 1.12 0.038 0.945
LDL-C (mmol/L) Lean 2.20 0.04 0.0001 Lean 1.31 0.048 < 0.0001 < 0.0001
Obese 2.65 0.09 Obese 2.11 0.078 < 0.0001
Leptin Lean 13.65 0.40 0.0001 Lean 11.70 0.464 < 0.0001 < 0.0001
Obese 35.78 1.78 Obese 39.94 2.59 0.181
Fasting ghrelin Lean 0.53 0.02 0.0001 Lean 0.57 0.016 < 0.0001 0.025
Obese 0.33 0.01 Obese 0.33 0.014 0.767
Fasting insulin (pmol/L) Lean 86.67 8.20 0.04 Lean 52.57 02.28 < 0.0001 < 0.0001
Obese 107.68 6.45 Obese 93.51 5. 37 0.094
Fasting Glucose (mmol) Lean 4.93 0.05 0.014 Lean 4.53 0.051 < 0.0001 < 0.0001
Obese 5.15 0.07 Obese 4.88 0.066 0.007
HOMA-IR (insulin resistance) Lean 2.807 0.27 0.034 Lean 1.49 0.070 < 0.0001 < 0.0001
Obese 3.492 0. 25 Obese 2.88 0.177 0.05
HOMA-S (insulin secretion) Lean 164.80 16.64 0.146 Lean 161.06 10.62 0.013 0.850
Obese 194. 25 11.97 Obese 207.19 14.64 0.49
  1. p1 = significance of the difference between lean and obese PCOS
  2. p2 = significance of the difference between lean and obese control
  3. p3 = significance of the difference between lean PCOS vs lean control and obese PCOS vs obese control
  4. HOMA Homeostatic model assessment