Fig. 3

The ratio of miR-221-3p and miR-222-3p and isolated low HDL-C phenotype. a The original Ct ratio of circulating miR-221-3p to miR-222-3p are significantly elevated in isolated low HDL-C phenotype. b Compared with the corresponding normal lipid phenotype, male subjects with isolated low HDL phenotype exhibit the increased miR-221-3p/222-3p ratio, while the female isolated low HDL-C phenotype have a increased trendence. c The original Ct ratio of miR-221-3p to miR-222-3p are inversely correlated with serum HDL-C levels in asymptomatic subjects (n = 174). The p value is adjusted using the Benjamini-Hochberg (BH) method in multiple comparisons