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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Lipidomic profiling of extracellular vesicles derived from prostate and prostate cancer cell lines

Fig. 4

EVs from tumourigenic cells show higher abundance of sphingolipid and sterol lipid species. a Most Cer species showed an overall increased abundance in NB26 and PC-3 EVs compared to RWPE1 EVs. However, several individual Cer and DHCer species including Cer(d16:1/20:0) and C18:0 DHCer had increased abundance in RWPE1 EVs. b Hexa-Cer species were more highly abundant in NB26 and PC-3 EVs, with both Hex3Cer species showing specific enrichment in NB26 EVs. c NB26 and PC-3 EVs had the highest overall abundance of SM species, with RWPE1 EVs only showing highest abundance in SM(43:1). d PC-3 EVs had the highest overall abundance of CE species. e Box plots of the representative sphingolipid and sterol lipid species Cer(d18:1/14:0), Hex2Cer(d18:1/16:0), SM(34:1) and CE (20:3) in EVs

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