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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis

Fig. 3

Effects of PGE2 on CGRP expression in cultured synovial cells, adipocytes, and the stromal vascular fraction. Synovial cells (SYC), adipocytes (Ad) and the stromal vascular fraction (SVF) were stimulated in vitro with PGE2 (10 μM) or serum-free medium without PGE2 (control, con) for 8 h. CGRP mRNA expression levels were evaluated by RT-PCR. All data are presented as the mean ± standard error (n = 8). *p < 0.05. a indicates a statistical difference between PGE2-stimulated and non-stimulated cells in each fraction. b indicates a statistical difference when compared to SYC under the same conditions

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