Table 3 The assess of contribution each clinical trials in association between CoQ10 supplementation and lipid profiles based on sensitivity analysis
Variable | Pre-sensitivity analysis | Upper & lower of effect size | Post-sensitivity analysis | ||||
|---|---|---|---|---|---|---|---|
No. of studies included | Pooled SMD (random effect) | 95% CI | Pooled SMD (random effect) | 95% CI | Excluded studies | ||
TC | 8 | −1.07 | − 1.94, − 0.21 | Upper | −0.26 | − 0.72, 0.18 | Sharifi (b) |
Lower | −1.30 | −2.29, −0.31 | Dai Y | ||||
LDL-C | 6 | −0.37 | −0.87, 0.13 | Upper | −0.14 | − 0.42, 0.12 | Pourmoghaddas |
Lower | −0.48 | − 1.04, 0.06 | Belardinelli | ||||
TG | 4 | 0.01 | −0.22, 0.24 | Upper | 0.16 | −0.15, 0.48 | Singh (2003) |
Lower | −0.05 | − 0.30, 0.19 | Belardinelli | ||||
HDL-C | 5 | 1.30 | 0.20, 2.41 | Upper | 1.67 | 0.32, 3.03 | Dai Y |
Lower | 0.47 | −0.13, 1.09 | Mohseni | ||||
Lp(a) | 3 | −1.12 | −2.84, 0.61 | Upper | − 0.03 | −0.39, 0.33 | Singh (1999) |
Lower | −1.79 | −4.98, 1.40 | Manolescu | ||||