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Table 2 The association between the risk of NAFLD and the genetic polymorphisms

From: Genetic polymorphisms associated with nonalcoholic fatty liver disease in Uyghur population: a case-control study and meta-analysis

SNP

WT Ho/ Ht/ VR Ho

VR Ho vs WT Ho

Ht vs WT Ho

Dominant model

Recessive model

VR allele vs WT allele

Control

NAFLD

P

OR (95%CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

rs1260326

115/145/43

103/149/65

0.03

1.69 (1.06–2.70)

0.09

1.15 (0.81–1.63)

0.15

1.27 (0.91–1.77)

0.04

1.56 (1.02–2.38)

0.04

1.27 (1.01–1.59)

rs780094

120/137/46

101/150/66

0.02

1.70 (1.08–2.70)

0.06

1.30 (0.92–1.85)

0.04

1.40 (1.01–1.95)

0.07

1.47 (0.97–2.22)

0.02

1.30 (1.04–1.63)

rs2954021

94/144/65

82/173/62

0.20

1.09 (0.69–1.73)

0.09

1.38 (0.95–1.99)

0.15

1.29 (0.91–1.83)

0.56

0.89 (0.60–1.32)

0.56

1.07 (0.85–1.34)

rs2228603

242/57/4

253/58/6

0.58

1.43 (0.40–5.15)

0.84

0.97 (0.65–1.46)

0.99

1.00 (0.68–1.49)

0.57

1.44 (0.40–5.16)

0.86

1.03 (0.73–1.46)

rs58542926

268/34/1

270/44/3

0.35

2.98 (0.31–28.81)

0.36

1.28 (0.80–2.07)

0.23

1.33 (0.83–2.13)

0.33

2.89 (0.30–27.89)

0.18

1.35 (0.87–2.09)

rs12137855

200/96/7

223/83/11

0.49

1.41 (0.54–3.71)

0.25

0.78 (0.55–1.10)

0.25

0.82 (0.58–1.15)

0.39

1.52 (0.58–3.97)

0.46

0.89 (0.67–1.20)

rs10883437

175/115/13

168/134/15

0.64

1.20 (0.56–2.60)

0.49

1.21 (0.88–1.68)

0.23

1.21 (0.88–1.67)

0.79

1.11 (0.52–2.37)

0.27

1.17 (0.89–1.53)

  1. OR odds ratio; VR variant; WT wild-type; Ht heterozygote; VR Ho, variant homozygote; WT Ho, wide-type homozygote