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Table 1 Physical characteristics, clinical data, etiology of the heart failure (HF) and medications used by patients with class I/II and III/IV heart failure (HF)

From: Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure

 

HF I/II (n = 25)

HF III/IV (n = 23)

p-value

Age (years)

63 ± 13

66 ± 11

0.359

Gender, n (%)

0.407

 Male

16 (64.0)

13 (56.5)

 

 Female

9 (36.0)

10 (43.5)

 

BMI (Kg/m2)

28 ± 5

24 ± 4

0.041

Coronary artery disease, n (%)

14 (56.0)

7 (30.4)

0.067

Ischemic heart disease, n (%)

9 (36.0)

4 (17.4)

0.130

Hypertension, n (%)

16 (64.0)

15 (65.2)

0.585

Diabetes mellitus, n (%)

7 (28.0)

4 (17.4)

0.300

Hyperlipidemia, n (%)

10 (40.0)

3 (13.0)

0.036

HF etiology, n (%)

 Hypertension

7 (28.0)

8 (34.8)

0.422

 Ischemic

9 (36.0)

4 (17.4)

0.130

 Dilated cardiomyopathy

6 (24.0)

7 (30.4)

0.430

 Myocarditis

3 (12.0)

2 (8.7)

0.541

 Idiopathic

0 (0)

2 (8.7)

0.224

Medication, n (%)

 ACE inhibitors

20 (80.0)

21 (91.3)

0.244

 Beta blockers

13 (52.0)

17 (73.9)

0.102

 Aldosterone antagonists

4 (16.0)

22 (95.7)

< 0.001

 Diuretics

16 (64.0)

15 (65.2)

0.585

 Antiplatelet

13 (52.0)

7 (30.4)

0.111

 Anticoagulants

1 (4.0)

3 (13.0)

0.273

 Antiarrhythmic

7 (28.0)

0 (0.0)

0.007

 Metformin

9 (36.0)

6 (26.1)

0.335

 Statina

10 (40.0)

3 (13.0)

0.036

  1. Frequencies distributions are expressed in number of cases (n) and percentage (%). Age and BMI are expressed as mean ± standard deviation. ACE angiotensin-converting enzyme, BMI body mass index
  2. aIn patients under statin use, the treatment was discontinued for 30 days before they were studied