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Table 3 Inflammatory cytokines concentrations data (pg/mL) of the group of patients with class I/II and III/IV heart failure (HF)

From: Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure

 

HF I/II (n = 25)

HF III/IV (n = 23)

p-value

p-value b

TNFα

4.45 ± 2.44 (1.29–9.68)

4.93 ± 3.65 (1.22–18.61)

0.733 a

0.546 c

IL-1β

1.10 ± 3.25 (0.19–16.64)

0.52 ± 0.36 (0.19–1.88)

0.611 a

0.280 c

IL-6

9.45 ± 13.04 (0.25–45.00)

13.61 ± 15.02 (0.29–60.86)

0.165 a

0.166 d

IL-8

5.30 ± 3.42 (1.41–14.86)

9.82 ± 8.35 (0.62–31.94)

0.025 a

0.027 c

MCP-1

140.17 ± 45.87 (67–233)

159.67 ± 58.22 (65–258)

0.206

0.220

  1. Values are expressed as mean ± standard deviation (min-max). TNFα tumor necrosis factor α, IL interleukin, MCP-1 monocyte chemotactic protein
  2. a Non-parametric Mann-Whitney U-test
  3. b All models were adjusted by BMI, hyperlipidemia and coronary artery disease; The analysis were performed using generalized linear models with normal distribution and identity link function
  4. c Generalized linear models with gamma distribution and identity link function
  5. d Generalized linear models with normal distribution and logarithmic link function